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TranscriptomicsMetabolic Reprogramming During Purine Stress in the Protozoan Pathogen Leishmania donovani
The ability of Leishmania to survive in their insect or mammalian host is dependent upon an ability to sense and adapt to changes in the microenvironment. However, little is known about the molecular mechanisms underlying the parasite response to environmental changes, such as nutrient availability....
ORGANISM(S): Leishmania donovani 
2014-02-01 | E-GEOD-48394 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast treated with hydrogen peroxide in fission yeast wild type and csx1 mutant cells
Time course experiments of hydrogen peroxide treated cells for both S. pombe wild type and csx1 mutant cells.
ORGANISM(S): Schizosaccharomyces pombe 
2004-10-01 | E-MEXP-176 | biostudies-arrayexpress
ProteomicsA post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells
While the transcriptional network of human embryonic stem cells (hESCs) has been extensively studied, relatively little is known about how post-transcriptional modulations determine hESC function. RNA-binding proteins play central roles in RNA regulation, including translation and turnover. Here we ...
ORGANISM(S): Homo sapiens (Human) 
2018-05-16 | PXD007270 | Pride
Shrna Lc-ms Hescs 
ProteomicsCo-immumnoprecipitation experiments to identify protein bindining partners of CSDE1
While the transcriptional network of human embryonic stem cells (hESCs) has been extensively studied, relatively little is known about how post-transcriptional modulations determine hESC function. RNA-binding proteins play central roles in RNA regulation, including translation and turnover. Here we ...
ORGANISM(S): Homo sapiens (Human) 
2018-05-16 | PXD007271 | Pride
Lc-ms Co-ip Hescs 
ProteomicsA post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells
We compared hESCs with their neuronal counterpart to quantify differences in the expression of cold-shock domain containing proteins. While the transcriptional network of human embryonic stem cells (hESCs) has been extensively studied, relatively little is known about how post-transcriptional modula...
ORGANISM(S): Homo sapiens (Human) 
2018-05-16 | PXD007738 | Pride
Comparison hescs versus their differentiated counterparts 
UnknownLysine ubiquitination and acetylation of human cardiac 20S proteasomes.
Not available
S-EPMC5094860 | biostudies-literature
UnknownAn observational study of system-level changes to improve the recording of very brief advice for smoking cessation in an inpatient mental health setting.
Not available
S-EPMC7183585 | biostudies-literature
UnknownActivation of the yeast Hippo pathway by phosphorylation-dependent assembly of signaling complexes.
Not available
S-EPMC3884217 | biostudies-literature
UnknownHeterozygous <i>RPA2</i> variant as a novel genetic cause of telomere biology disorders.
Not available
S-EPMC11444173 | biostudies-literature
UnknownProteinInferencer: Confident protein identification and multiple experiment comparison for large scale proteomics projects.
Not available
S-EPMC4630118 | biostudies-literature
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