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ProteomicsA new long-acting tissue kallikrein ameliorates ischemic stroke injury by inhibiting HMGB1-related neuroinflammation and apoptosis
The proteomics analysis of total proteins extracted from the cerebral ischemic penumbra tissues of different groups three days after MCAO
ORGANISM(S): Mus Musculus 
PXD042777 |
ProteomicsA new long-acting tissue kallikrein ameliorates ischemic stroke injury by inhibiting HMGB1-related neuroinflammation and apoptosis-ip
Coimmunoprecipitation, detect binding protein of HMGB1 in primary microglials in control and LPS group
ORGANISM(S): Mus Musculus 
PXD042778 |
ProteomicsVersican regulating viscoelasticity drives pleural fibrosis via mechanotransductive signaling
Extracellular matrix (ECM) disorder was considered as the result of fibrosis, but it is recently recognized that fibrotic ECM activates a profibrotic positive feedback loop and contributes to development of fibrosis. Versican, an ECM component, participates in cell-ECM interaction and ECM regenerati...
ORGANISM(S): Homo Sapiens 
2026-01-15 | PXD073100 |
ProteomicsPBRM1-deficient PBAF complexes target de novo genomic loci to activate pro-survival genes in clear cell renal cell carcinoma (PBRM1 dataset)
PBRM1 is lost in 40% of clear cell renal cell carcinomas (ccRCC) and the combined loss of VHL and PBRM1 drives ccRCC tumorigenesis. PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and despite its well-established role as a tumor suppressor, we have limited under...
ORGANISM(S): Homo Sapiens (human) 
2021-07-24 | PXD020554 | JPOST Repository
ProteomicsPBRM1-deficient PBAF complexes target de novo genomic loci to activate pro-survival genes in clear cell renal cell carcinoma (BRG1 dataset)
PBRM1 is lost in 40% of clear cell renal cell carcinomas (ccRCC) and the combined loss of VHL and PBRM1 drives ccRCC tumorigenesis. PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and despite its well-established role as a tumor suppressor, we have limited under...
ORGANISM(S): Homo Sapiens (human) 
2021-07-24 | PXD020553 | JPOST Repository
ProteomicsSpatial-region-resolved proteomic map reveals mechanism of COVID-19-associated heart injury
Coronavirus disease 2019 (COVID-19) induces diverse clinical manifestations accompanied by multi-organ dysfunction. Of these, heart complications are the most life threatening. Direct myocardial and vascular injuries due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) drive systemic ...
ORGANISM(S): Homo Sapiens 
2022-01-26 | PXD031249 |
UnknownThe power of genetic diversity in genome-wide association studies of lipids.
Not available
S-EPMC8730582 | biostudies-literature
UnknownUse of Telemedicine for Postdischarge Assessment of the Surgical Wound: International Cohort Study, and Systematic Review With Meta-analysis.
Not available
S-EPMC10174106 | biostudies-literature
UnknownSurgical site infection after gastrointestinal surgery in children: an international, multicentre, prospective cohort study.
Not available
S-EPMC7716674 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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