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UnknownUnexpected mutations occurred in CRISPR/Cas9 edited Drosophila analyzed by deeply whole genomic sequencing.
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S-EPMC11002691 | biostudies-literature
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
ProteomicsAqueous humour proteomic analysis of acute angle-closure glaucoma with visual field loss
original data of Aqueous humour proteomic analysis of acute angle-closure glaucoma with visual field loss.
ORGANISM(S): Homo Sapiens 
2021-02-05 | PXD024028 |
ProteomicsMouse ovarian Proteomic analysis after Cigarette smoke exposure
A total of 30 days of exposure to cigarette smoke (CS) or indoor air was given to 8- 23 week-old female C57BL/6 mice, then proteomics analyses were used to determine the 24 impact of CS on ovarian reserve.
ORGANISM(S): Mus Musculus 
2023-12-21 | PXD048026 |
ProteomicsProteomic study of aqueous humor and its application in the treatment of neovascular glaucoma
We provided a comprehensive AH proteome analysis, and expanded the profile of human AH proteome. The differential AH proteomic analysis of NVG treatment indicated that AH proteome can reflect the pathophysiological changes in drug intervention.
ORGANISM(S): Homo Sapiens 
PXD020177 |
ProteomicsProteome characterization of glaucoma aqueous humour
This work describes a proteomic analysis for different types of glaucoma (PACG, NVG) and age-related cataract as control. The AH samples were recruited from 175 individual patients with PACG, NVG and age-related cataract. First, in discovery cohort the AH proteome characteristics of PAACG, PCACG and...
ORGANISM(S): Homo Sapiens 
PXD027686 |
ProteomicsCharacterization of LC-MS based urine metabolomics in healthy children and adults
In this study, we provided a comprehensive lifespan characterization of urine metabolomics in a cohort of 348 healthy children and 315 adults aged 1 to 70 years using liquid chromatography coupled with high resolution mass spectrometry.
ORGANISM(S): Homo Sapiens 
PXD034390 |
ProteomicsARIH1 Signaling Promotes Anti-tumor Immunity by Targeting PD-L1 for Proteasomal Degradation
We find EGFR inhibitors promote PD-L1 ubiquitination and proteasomal degradation following GSK3α-mediated phosphorylation of Ser279/Ser283.
ORGANISM(S): Homo Sapiens 
2021-03-01 | PXD024452 |
ProteomicsLow-dose metformin targets the lysosome-AMPK pathway through PEN2
Metformin is the most prescribed anti-diabetic medicine, and has also been shown to have other various benefits, such as anti-aging and anti-cancer effects. For clinical doses of metformin, it is known that AMPK plays a major role; however, the direct molecular target of metformin remains unclear. H...
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-12-01 | PXD030090 |
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