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TranscriptomicsTranscription profiling of mouse Scl -/- yolk sac cell line after reintroduction of Scl by protein transduction
Expression profile of Scl -/- yolk sac cell line after reintroduction of Scl
ORGANISM(S): Mus musculus 
2008-01-09 | E-TABM-397 | biostudies-arrayexpress
TranscriptomicsThe role of the yolk sac in human fetal development and identification of a hepatocyte-like cell in the human yolk sac
The human yolk sac (YS) is an extra-embryonic tissue critical for early prenatal life development. It is the first site of haematopoiesis where progenitors differentiate from endoderm within blood islands of the yolk sac contributing initially to primitive erythropoiesis and in subsequent waves to e...
ORGANISM(S): Homo sapiens 
2023-03-01 | E-MTAB-10552 | biostudies-arrayexpress
TranscriptomicsThe role of the yolk sac in human fetal development and identification of a hepatocyte-like cell in the human yolk sac (SS2)
The human yolk sac (YS) is an extra-embryonic tissue critical for early prenatal life development. It is the first site of haematopoiesis where progenitors differentiate from endoderm within blood islands of the yolk sac contributing initially to primitive erythropoiesis and in subsequent waves to e...
ORGANISM(S): Homo sapiens 
2023-03-01 | E-MTAB-10888 | biostudies-arrayexpress
TranscriptomicsExpression data from Tnrc6a (GW182) mutant yolk sac
GW182 (Tnrc6a) is a key component of RISC (miRNA-Induced Silencing Complex) that plays a critical role in miRNA-mediated gene silencing. Here, we show that GW182 is expressed in the yolk sac endoderm, and that gene-trap disruption of GW182 leads to growth arrest of yolk sac endoderm, impaired hemato...
ORGANISM(S): Mus musculus 
2011-08-31 | E-GEOD-30244 | biostudies-arrayexpress
TranscriptomicsKLF2-Regulated Gene Expression in Mouse Embryonic Yolk Sac Erythroid Cells
KLF2 is a Krüppel-like zinc-finger transcription factor required for blood vessel, lung, T-cell, and erythroid development. KLF2-/- mice die by embryonic day 14.5 (E14.5), due to hemorrhaging and heart failure. Embryonic -like globin gene expression is reduced in KLF2-/- embryos compared to wildtype...
ORGANISM(S): Mus musculus 
2011-03-02 | E-GEOD-27602 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of rudhira null embryo and yolk sac at 9.5 dpc
Rudhira is essential for mouse developmental angiogenesis and tissue morphogenesis. Embryos lacking endothelial rudhira die at mid-gestation with vascular patterning defects. Rudhira mutant yolk sac endothelial cells show slow and random migration. So to identify key signaling pathways perturbed in ...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-69204 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression between wild type, Notch1-activated, and RBPJ loss-of-function embryonic mouse yolk sac tissue at E9.5
The signaling cascades that direct the morphological differentiation of the vascular system during early embryogenesis are not well defined. To further understand the role of Notch signaling during endothelial differentiation, this study uses both an in vivo gain-of-function and in vivo loss-of-fun...
ORGANISM(S): Mus musculus 
2010-07-07 | E-GEOD-22418 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of inducible ES cells overexpressing Etv2 (induced for 12 hours at day 3 of differentiation)
During embryogenesis, the endothelial and the hematopoietic lineages first appear during gastrulation in the blood island of the yolk sac. We have previously reported that an Ets variant gene 2 (Etv2/ER71) mutant embryo lacks hematopoietic and endothelial lineages, however, the precise roles of Etv2...
ORGANISM(S): Mus musculus 
2012-07-03 | E-GEOD-37658 | biostudies-arrayexpress
TranscriptomicsCapacity of yolk sac macrophages, fetal liver and adult monocytes to colonize an empty niche and develop into functional tissue resident macrophages
Tissue-resident macrophages can derive from yolk sac macrophages, fetal liver monocytes or adult bone marrow monocytes. Whether these precursors can give rise to transcriptionally identical alveolar macrophages is unknown. Here, we transferred traceable yolk sac macrophages, fetal liver monocytes, a...
ORGANISM(S): Mus musculus 
2016-03-01 | E-GEOD-76999 | biostudies-arrayexpress
ProteomicsLC-MS/MS of differentiated bone marrow and Yolk sac macrophages
We immortalized hematopoietic progenitors from Yolk sac (YS) and bone marrow (BM) using conditional homeobox protein Hox-B8 (Hoxb8) and carried out global protein profiling using a bottom-up approach.
ORGANISM(S): Mus musculus (Mouse) 
2025-08-07 | PXD026916 | Pride
Lc-ms/ms Hoxb8 Bone marrow Yolk sac Macrophages 
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