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UnknownSkeletal muscle-specific DJ-1 ablation-induced atrogenes expression and mitochondrial dysfunction contributing to muscular atrophy.
Not available
S-EPMC10570112 | biostudies-literature
MetabolomicsTreatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics
Introduction: Obestatin is a controversial gastrointestinal peptide purported to have metabolic actions. Objectives: This study investigated whether treatment with a stable obestatin analogue (PEG-OB(Cys10, Cys13) changed plasma metabolite levels firstly in lean and subsequently in diet-induced obes...
2017-07-25 | MTBLS334 | MetaboLights
ProteomicsLuminal cerebrovascular proteomic changes during aging
The blood-brain barrier (BBB) is highly specialized to protect the brain from harmful circulating factors in the blood and maintain brain homeostasis. However, during aging and neurodegenerative disease, the BBB undergoes numerous molecular changes that can promote inflammation and disease pathogene...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-17 | PXD043964 | Pride
Brain Mouse Vasculature Bbb Aging 
UnknownPharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Male Mice.
Not available
S-EPMC11741898 | biostudies-literature
MetabolomicsCroquemort elicits activation of the immune deficiency pathway in ticks
The immune deficiency (IMD) pathway directs host defense in arthropods upon bacterial infection. In Pancrustacea, peptidoglycan recognition proteins sense microbial moieties and initiate nuclear factor-κB-driven immune responses. Proteins that elicit the IMD pathway in non-insect arthropods remain e...
2023-04-27 | MTBLS686 | MetaboLights
ProteomicsPiezo1 integration of vascular architecture with physiological force LC-MSMS
The mechanisms by which physical forces regulate cells to determine complexities of vascular structure and function are enigmatic. Here we show the role the ion channel subunit Piezo1 (FAM38A). Disruption of mouse Piezo1 gene disturbed vascular development and was embryonic lethal within days of the...
ORGANISM(S): Homo sapiens (Human) 
2014-08-08 | PXD001099 | Pride
Shear stress Human Mouse Piezo1 Label-free Phosphoproteomics Huvec Vascular architecture 
UnknownIndividualized therapy for persistent asthma in young children.
Not available
S-EPMC5148729 | biostudies-literature
UnknownAcetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma.
Not available
S-EPMC5085065 | biostudies-literature
UnknownInclusion of a core patient-reported outcomes battery in adolescent and young adult cancer clinical trials.
Not available
S-EPMC9830479 | biostudies-literature
UnknownTelescope: an interactive tool for managing large-scale analysis from mobile devices.
Not available
S-EPMC6977584 | biostudies-literature
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