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TranscriptomicsTranslocations Activating IRF4 Identify a Subtype of Germinal-Center-Derived B-cell Lymphoma Affecting Predominantly Children and Young Adults
Background: Germinal center B-cell (GCB) lymphomas are common in children and adults. The prognosis strongly depends on age. Subgroups of GCB-lymphomas are characterized by chromosomal translocations affecting immunoglobulin (IG) loci leading to oncogene deregulation. Methods: Novel IG translocation...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-22470 | biostudies-arrayexpress
TranscriptomicsP12365 - A/J COPD - Parenchyma
Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disorder that is the result of extended exposure of the airways to noxious stimuli, principally cigarette smoke (CS). The mechanisms through which COPD evolves are not fully understood though it is believed that the disease process includ...
ORGANISM(S): Mus musculus 
2014-05-14 | E-MTAB-1426 | biostudies-arrayexpress
UnknownFluvastatin Reduces Glucose Tolerance in Healthy Young Individuals Independently of Cold Induced BAT Activity.
Not available
S-EPMC8631514 | biostudies-literature
UnknownReward-related neural activation during social media exposure in young women with non-suicidal self-injury: evidence for a continuum of severity in the reward network.
Not available
S-EPMC12373755 | biostudies-literature
UnknownA randomized controlled trial of the GLP-1 receptor agonist dulaglutide in primary polydipsia.
Not available
S-EPMC8516458 | biostudies-literature
UnknownFertility-Sparing Approaches in Atypical Endometrial Hyperplasia and Endometrial Cancer Patients: Current Evidence and Future Directions.
Not available
S-EPMC8910633 | biostudies-literature
MetabolomicsIntegration of magnetic resonance imaging and protein and metabolite CSF measurements to enable early diagnosis of secondary progressive multiple sclerosis

Molecular networks in neurological diseases are complex. Despite this fact, contemporary biomarkers are in most cases interpreted in isolation, leading to a significant loss of information and power. We present an analytical approach to scrutinize and combine information from biomarkers originati...

2018-08-13 | MTBLS558 | MetaboLights
TranscriptomicsThe Influence of Sleep Deprivation on Hippocampal CA1 Gene Expression: Relation to Stress and Aging
Sleep deprivation (SD) in young adults is associated with metabolic, stress and cognitive responses that are also characteristic of brain aging. Given that sleep architecture changes with age, including increased fragmentation and decreased slow wave activity, it seems reasonable to investigate pote...
ORGANISM(S): Rattus norvegicus 
2012-07-16 | E-GEOD-34424 | biostudies-arrayexpress
ProteomicsProteomic analysis of successful and biologically compromised bone fracture healing
Bone fracture healing shows approximately 10-15% non-unions, although theoretically it has the potential of scarless regeneration. With regards to our aging society, a better understanding of the healing process is needed to allow for more sophisticated treatment options. Particular the early phase,...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-05-10 | PXD020085 | Pride
Lc-ms Bone Rattus norvegius 
TranscriptomicsmRNA-Seq of daphnia magna juveniles exposed to different sub-lethal concentrations of Fipronil in a modified acute immobilisation test below against untreated control groups
The aim of this mRNA expression profiling experiment was to screen for ecotoxicogenomic fingerprints in juvenile daphnids (daphnia magna) as aquatic vertebrate non-target model exposed to sub lethal concentrations of Fipronil. Fipronil is a widely used insecticide applied for crop protection against...
ORGANISM(S): Daphnia magna 
2021-08-04 | E-MTAB-9829 | biostudies-arrayexpress
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