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GenomicsGenome wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer
Background: 5-hydroxymethylcytosine (5-hmC) is a recently discovered epigenetic modification that is altered in cancers. Genome wide assays for 5-hmC determination are needed as many of the techniques commonly used to assay 5-methylcytosine (5-mC), including conventional methyl-sensitive restriction...
ORGANISM(S): Homo sapiens 
2013-07-30 | E-GEOD-42723 | biostudies-arrayexpress
GenomicsTet1 is a tumor suppressor of hematopoietic malignancy
Epigenetic pathways that regulate DNA methylation and chromatin modifications are frequently found to be dysregulated in human cancers. The TET methylcytosine dioxygenase 1 (TET1) enzyme is an important regulator of hydroxymethylcytosine (5hmC) in embryonic stem cells, neural progenitors,adult cells...
ORGANISM(S): Mus musculus 
2015-04-12 | E-GEOD-65895 | biostudies-arrayexpress
MetabolomicsA Novel Approach to Characterize the Lipidome of Marine Archaeon Nitrosopumilus maritimus by Ion Mobility Mass Spectrometry

Archaea are differentiated from the other two domains of life by their biomolecular characteristics. One such characteristic is the unique structure and composition of their lipids. Characterization of the whole set of lipids in a biological system (the lipidome) remains technologically challengi...

2021-12-16 | MTBLS3714 | MetaboLights
UnknownHeregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.
Not available
S-EPMC4414164 | biostudies-literature
UnknownDisruption of theta-timescale spiking impairs learning but spares hippocampal replay.
Not available
S-EPMC12458185 | biostudies-literature
UnknownCo-occurring defect analysis: A platform for analyzing birth defect co-occurrence in registries.
Not available
S-EPMC7814855 | biostudies-literature
UnknownDissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology.
Not available
S-EPMC5490491 | biostudies-literature
UnknownEEG biomarkers of activation of the lymphatic drainage system of the brain during sleep and opening of the blood-brain barrier.
Not available
S-EPMC9841170 | biostudies-literature
UnknownA Functional Role for Antibodies in Tuberculosis.
Not available
S-EPMC5526202 | biostudies-literature
UnknownReprogramming to recover youthful epigenetic information and restore vision.
Not available
S-EPMC7752134 | biostudies-literature
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