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ProteomicsRegulation of mitophagy by Fis1 and Fascin1-organized actin
Mitophagy, the autophagic degradation of mitochondria, plays a central role in controlling the quality and quantity of mitochondria, thereby ensuring cellular health. The mitochondrial outer membrane protein Fis1 is important for several types of mitophagy, but its mechanism of action remains unclea...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-07 | PXD062948 | Pride
Mitophagy Fascin1 Fis1 Mitochondria Actin filaments 
ProteomicsQuantification of host proteomic responses to hepatitis E virus replication facilitated by pregnancy serum
In this study, the differences in the proteomics of HEV-infected HepG2 cells supplemented with fetal bovine serum (FBS) from those of HEV-infected HepG2 cells supplemented with serum from women in their third trimester of pregnancy were quantified by using isobaric tags for relative and absolute qua...
ORGANISM(S): Hepatitis E Virus 
2022-09-16 | PXD036836 |
Metabolomics2E,4E-decadienoic acid, a novel anti-oomycete agent from co-culture of Bacillus subtilis and Trichoderma asperellum

Phytophthora nicotianae is an oomycete pathogen of global significance threatening many important crops. It is mainly controlled by chemosynthetic fungicides, which endangers ecosystem and human health; thus, there is an urgent need to explore alternatives for these fungicides. In this s...

2022-08-01 | MTBLS5405 | MetaboLights
ProteomicsSkeletal muscle cell protein dysregulation highlights the pathogenesis mechanism of myopathy-associated p97/VCP R155H mutations
p97/VCP, a hexametric member of the AAA-ATPase superfamily, has been associated with a wide range of cellular protein pathways, such as proteasomal degradation, the unfolding of polyubiquitinated proteins, and autophagosome maturation. Autosomal dominant p97/VCP mutations cause a rare hereditary mul...
ORGANISM(S): Homo sapiens (Human) 
2023-07-23 | PXD044004 | Pride
Ibmpfd/als Myopathy Ipscs R155h mutation. Vcp/p97 Skeletal muscle 
TranscriptomicsThe Rpd3 Core Complex is a Chromatin Stabilization Module
The S. cerevisiae Rpd3 large (Rpd3L) and small (Rpd3S) histone deacetylase (HDAC) complexes are prototypes for understanding transcriptional repression in eukaryotes [1]. The current view is that they function by deacetylating chromatin, thereby limiting accessibility of transcriptional factors to t...
ORGANISM(S): Saccharomyces cerevisiae 
2012-01-01 | E-GEOD-33829 | biostudies-arrayexpress
UnknownClinical characteristics and risk factors for readmission after deep anterior lamellar keratoplasty: a nationwide, cross-sectional, multicenter study.
Not available
S-EPMC11984012 | biostudies-literature
ProteomicsProteins that interact with FGD5 in MDA-MB-231
To examine the presence of the proteins that interact with FGD5 in triple negative breast cancer cell line
ORGANISM(S): Homo Sapiens 
2021-02-19 | PXD024266 |
ProteomicsProteomics Analysis of Human Obesity and Metabolic Syndrome Serum
Metabolic syndrome (MS) is a cluster of risk factors that can lead to a disorder of energy utilization and storage and raises risk for heart disease and other health problems. Obesity is a prevalent metabolic disorder in the developed countries and in large parts of developing world that is one of m...
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035512 |
TranscriptomicsFate and State Transitions during Human Blood Vessel Organoid Development: Time Course
Human blood vessel organoids (hBVOs) derived from human pluripotent stem cells have emerged as a novel system to understand human vascular development, model disorders, and develop regenerative therapies. However, it was unclear which molecular states constitute hBVOs and how cells differentiate and...
ORGANISM(S): Homo sapiens 
2025-03-21 | E-MTAB-14807 | biostudies-arrayexpress
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