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ProteomicsLabel-free LC-MSMS proteomics for P30 Acox1 WT vs KO
Background: Dyslipidemia is a significant contributor to many eye diseases and the lipid processing pathways are not well understood. Peroxisomes oxidize very long-chain, monocarboxylic and dicarboxylic fatty acids. Genetic mutations in peroxisomal proteins may lead to severe neural retinal degenera...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-15 | PXD055240 | Pride
Lc-msms Retinas Peroxisome Acox1 
ProteomicsCombined dietary omega-3 and omega-6 fatty acids protect against hyperglycemia-associated retinopathy in neonatal mice
Introduction: Retinopathy of prematurity (ROP) with early vessel loss (Phase I) followed by uncontrolled vessel growth (Phase II) causes visual impairment in premature infants. Although supplementation with n-3 docosahexaenoic acid (DHA) alone has mixed results to prevent ROP, combined supplementati...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD061307 | Pride
Retinopathy of prematurity Dha Retinal vasculature Postnatal hyperglycemia 
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