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UnknownA Target-Triggered Emission Enhancement Strategy Based on a Y-Shaped DNA Fluorescent Nanoprobe with Aggregation-Induced Emission Characteristic for microRNA Imaging in Living Cells.
Not available
S-EPMC10004006 | biostudies-literature
MetabolomicsBCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS (untargeted lipidomics)

Premature ovarian insufficiency (POI) is a disease featured by early menopause before 40 years of age, accompanied by an elevation of follicle-stimulating hormone. Though POI affects many aspects of women's health, its major causes remain unknown. Many clinical studies have shown that POI patient...

2024-09-26 | MTBLS6249 | MetaboLights
MetabolomicsMultiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights
ProteomicsUbiquitination sites on MIDN identified by mass spectrometry analysis
In E. coli, the pACYC-HA-Ub-E1 (UBA1)-UbcH5A-RNF126 and pET-22b-MIDN-His₆ plasmids were co-transformed. After IPTG induction to express all proteins required for ubiquitination, His-tagged MIDN was enriched with Ni-NTA resin and subjected to mass-spectrometric mapping of its ubiquitin-modified sites...
ORGANISM(S): Homo sapiens (Human) 
2026-06-01 | PXD069387 | Pride
Ubiquitination sites Midn 
MetabolomicsBCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS (targeted metabolomics)

Premature ovarian insufficiency (POI) is a disease featured by early menopause before 40 years of age, accompanied by an elevation of follicle-stimulating hormone. Though POI affects many aspects of women's health, its major causes remain unknown. Many clinical studies have shown that POI patient...

2024-09-26 | MTBLS6267 | MetaboLights
UnknownHealth literacy and exercise-focused interventions on clinical measurements in Chinese diabetes patients: A cluster randomized controlled trial.
Not available
S-EPMC6933227 | biostudies-literature
TranscriptomicsRNA Sequencing Analysis Generates Comprehensive Transcriptomic Landscape and Identifies PTK6 as a Novel Tumor Suppressor Gene in Esophageal Squamous Cell Carcinoma
We performed the integrative transcriptome analysis of human esophageal squamous cell carcinoma (ESCC) using Illumina high-throughput sequencing. A total of 187 million 38bp sequencing reads were generated containing 7 billion bases for three pairs of matched patient-derived ESCC clinical specimens ...
ORGANISM(S): Homo sapiens 
2012-06-01 | E-GEOD-29968 | biostudies-arrayexpress
UnknownEffects of transcranial direct current stimulation combined with acupuncture therapy on brain network functional connectivity in patients with knee osteoarthritis: a single-center randomized controlled trial.
Not available
S-EPMC12257676 | biostudies-literature
Proteomicsthe proteomic data of systematic organs of CHIKV-infected mouse and rhesus monkey
this proteomic data is compromised of 72 samples from 6 mouses and 6 rhesus monkeys. CHIKV, as a mosquito-based virus, is well known to pose threat to muscles and joints, with its symptoms being called chikunkunya fever, whereas its impact on other organs after infection is not completely understood...
ORGANISM(S): Mus musculus (Mouse) Macaca mulatta (Rhesus macaque) 
2024-05-31 | PXD048726 | Pride
Brain Lung Liver Kidney Heart Spleen 
UnknownYHSeqY3000 panel captures all founding lineages in the Chinese paternal genomic diversity database.
Not available
S-EPMC11752814 | biostudies-literature
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