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Enhancer retargeting at the PAX5/ZCCHC7 locus
The underlying mechanism by which ZCCHC7 exerted carcinogenesis and its potential targets in CRC
Transcriptome analysis of ZCCHC7 wildtype(WT) and overexpression (OE) in colorectal cancer
An RIP experiment was performed in RKO cells using ZCCHC7 antibody as bait. The position of peak summit around transcript start sites of genes can predict the interaction sites of protein and gene. We compared the peak summit of RKO WT and RKO ZCCHC7-OE cells to find the differences between RKO WT c...
ORGANISM(S): Homo sapiens 
2025-03-01 | GSE234581 | GEO
Transcriptome sequencing was used to analyze changes in related signaling pathways and gene expression in colon cancer cells when ZCCHC7 was overexpressed .
ORGANISM(S): Homo sapiens 
2024-10-08 | GSE189558 | GEO
An RIP experiment was performed in RKO cells using SRSF1 antibody as bait. The position of peak summit around transcript start sites of genes can predict the interaction sites of protein and gene. We compared the peak summit of RKO WT and RKO ZCCHC7-OE cells to find the differences between RKO WT ce...
ORGANISM(S): Homo sapiens 
2025-03-01 | GSE234580 | GEO
The pancreatic endocrine cells, particularly the insulin secreting β-cells, adapt to pregnancy by increasing cell mass, size and altering secretory patterns. Since most studies utilize rodent models, translating findings to human pregnancy remains challenging. In this work, we performed an extensive...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-05-26 | PXD077246 | Pride
We have characterized several stages of normal human B cell development in adult bone marrow by gene expression profiling of hemopoietic stem cells, early B (E-B), pro-B, pre-B, and immature B cells, using RNA amplification and Lymphochip cDNA microarrays (n = 6). Hierarchical clustering of 758 diff...
ORGANISM(S): Homo sapiens 
2 kinds of SU-DHL-10 cell clones (Pax5-TSS2mut/deletion) were generated to investigate enhancer relocation, we campared 4C-seq data between the Pax5-TSS2mut/deletion clones and wild type SU-DHL-10.
ORGANISM(S): Homo sapiens 
2023-09-22 | GSE210888 | GEO
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