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UnknownDifferences in the prevalence of cardiovascular and metabolic diseases coinciding with clinical subtypes of obstructive sleep apnea.
Not available
S-EPMC9849430 | biostudies-literature
UnknownHepatitis B virus infection and genotype in asymptomatic people from 10 ethnic groups in Yunnan, China.
Not available
S-EPMC4658612 | biostudies-literature
ProteomicsInferior Temporal Gyrus in Human Ageing: a Quantitative Protein Profiling Work based on Chinese Human Brain Bank
The temporal lobe is the cerebral cortex with critical function. The superior and middle gyrus of temporal lobe have been well studied, however, present perceptions on inferior temporal gyrus remains limited. The understanding of age-related protein profile change in human inferior temporal gyrus ha...
ORGANISM(S): Homo sapiens (Human) 
2015-12-07 | PXD002528 | Pride
Inferior temporal gyrus  tmt  proteomics  ageing  chinese human brain bank. 
ProteomicsProtein Profile Changes in the Frontotemporal Lobes in Human Severe Traumatic Brain Injury
Severe traumatic brain injury (sTBI) is a serious public health issue with high morbidity and mortality rates. Previous proteomic studies on sTBI have mainly focused on human cerebrospinal fluid and serum, as well as on brain protein changes in murine models. However, human proteomic data in sTBI br...
ORGANISM(S): Homo sapiens (Human) 
2016-04-15 | PXD002783 | Pride
Severe traumatic brain injury  tmt (tandem mass tags)  human  proteomics 
ProteomicsALKBH7, a mitochondrial member of AlkB family, binds histones in vitro, part 2
Human genome encodes 9 AlkB family members, one of which is ALKBH7. In this study, we found recombinant ALKBH7 could bind bulk histones in GST pull-down and attenuate the signal of H4K20me2 in demethylation assays. With mass spectrometry, we also identified several potential ALKBH7-interacting prote...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD008319 | Pride
Alkbh7 mitochondrion histone 
ProteomicsALKBH7, a mitochondrial member of AlkB family, binds histones in vitro, part 1
Human genome encodes 9 AlkB family members, one of which is ALKBH7. In this study, we found recombinant ALKBH7 could bind bulk histones in GST pull-down and attenuate the signal of H4K20me2 in demethylation assays. With mass spectrometry, we also identified several potential ALKBH7-interacting prote...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD008318 | Pride
Alkbh7 mitochondrion histones 
ProteomicsTMT-labeled quantitative protein profiling of hippocampus during human aging
Human hippocampus is one of the critical brain regions affected by aging. However, a fully understanding of aging-related changes in protein profiles in human hippocampus has not been well described, especially for the Chinese population. With the newly founded human brain bank in Chinese Academy of...
ORGANISM(S): Homo sapiens (Human) 
2016-04-13 | PXD001987 | Pride
Human Aging Hippocampus 
ProteomicsFocal adhesion and NRF2 pathway regulate left-right asymmetries of rhesus hippocampus aging: relevance to human hippocampus aging and Alzheimer’s disease
Left-right asymmetry is a basic character of aging brain; however, the molecular foundation of the left-right asymmetry remains unclear. The morphology, physiology and behavior of rhesus aging are obviously similar to human aging, but the aging-rate of rhesus is roughly three times as fast as human,...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2020-01-23 | PXD011398 | Pride
Rhesus Human Evolution Alzheimer's disease Aging 
ProteomicsComparative analysis of maca (Lepidium meyenii) proteome profiles reveals insights into response mechanisms of herbal plants to high-temperature stress
High-temperature stress (HTS) is one of the main environmental stresses that limit plant growth and crop production in agricultural systems. Maca (Lepidium meyenii) is an important high-altitude herbaceous plant adapted to a wide range of environmental stimuli such as cold, strong wind and UV-B expo...
ORGANISM(S): Lepidium meyenii 
2020-08-25 | PXD021042 | Pride
High-temperature stress Stress response Tandem mass tag Molecular mechanism Maca 
ProteomicsALKBH7, a mitochondrial member of AlkB family, binds histones in vitro, part 3
Human genome encodes 9 AlkB family members, one of which is ALKBH7. In this study, we found recombinant ALKBH7 could bind bulk histones in GST pull-down and attenuate the signal of H4K20me2 in demethylation assays. With mass spectrometry, we also identified several potential ALKBH7-interacting prote...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD008320 | Pride
Alkbh7 mitochondrion histone 
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