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ProteomicsDeletion of vp0057 impacts the proteome profile in Vibrio parahaemolyticus
Using bioinformatics analysis, we found that VP0057 may be a potential Ser/Thr protein kinase with phosphorylation activity. Thus, we constructed the vp0057-deletion mutant (∆vp0057) from the wild-type V. parahaemolyticus serotype O3:K6 and employed a mass spectrometry-based proteomic strategy to ch...
ORGANISM(S): Vibrio Parahaemolyticus Rimd 2210633 
2020-09-30 | PXD021775 |
ProteomicsImpacts of Ser/Thr protein kinase Stk1 on proteome, twitching motility and competitive advantage in Pseudomonas aeruginosaImpacts of Ser/Thr protein kinase Stk1 on proteome, twitching motility and competitive advantage in Pseudomonas aeruginosa
Pseudomonas aeruginosa is a ubiquitous Gram-negative bacterium in the environment and a leading cause of nosocomial infections worldwide. Therefore, it is listed by the World Health Organization as one of the human pathogens that urgently need to develop new antibacterial drugs. Recent findings have...
ORGANISM(S): Pseudomonas aeruginosa PAK 
2021-07-07 | PXD027148 | Pride
Stk1 Ser/thr protein kinase Twitching motility Competitive advantage Pseudomonas aeruginosa. Proteome 
ProteomicsProteome-wide Hyposuccinylation of Esophageal Squamous Cell Cancer to Promotion of Tumor Metabolism and Migration
We identify abnormal protein and post-translational modification (PTM) pathways, including significantly downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways inextricably linked with can...
ORGANISM(S): Homo Sapiens 
2020-09-18 | PXD021567 |
ProteomicsHistone PTMs dataset for Hyposuccinylation Derived from Abnormal Metabolism Promotes the Cell Migration of Esophageal Squamous Cell Cancer
We identify abnormal protein and post-translational modification (PTM) pathways, including many downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways and the reduced succinyl-CoA may lead...
ORGANISM(S): Homo Sapiens 
2020-09-26 | PXD021700 |
ProteomicsProteomics of intestine in simulated microgravity rats
After 14 days simulated microgravity，rats jejunal mucosa was taken for proteomic study. A total of 1826 proteins were detected, and 335 differentially expressed proteins were detected, of which 190 were up-regulated and 145 were down-regulated.
ORGANISM(S): Rattus Norvegicus 
2020-09-17 | PXD021522 |
ProteomicsTemporal proteomics characterization of COVID-19 patient sera
We enrolled 37 SARS-CoV-2 positive patients including 17 short course (SC) COVID-19 patients (twice viral RNA detection negative over 24 hrs) and 20 COVID-19 long course (LC) COVID-19 patients. We also included 35 SARS-CoV-2 negative patients as control group. We collected 224 inactive serum samples...
ORGANISM(S): Homo Sapiens 
2022-07-26 | PXD035471 |
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