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ProteomicsPlasma Proteomic Characterization of Colorectal Cancer Patients with FOLFOX Chemotherapy
Colorectal Cancer (CRC) is one of most common cancers in the world and a main treatment in postoperative chemotherapy is oxaliplatin and fluorouracil (FOLFOX), But the effect is different among CRC patients. In this study, LC-MS/MS strategy was used to profile the plasma proteome in FOLFOX benefit a...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD044201 | Pride
Human plasma proteome  sisprot  lc-ms/ms  random forest  prm validation 
ProteomicsD283 MED, a cell line derived from peritoneal metastatic medulloblastoma — a good choice for missing protein discovery
Our goal is the identification of more and more missing proteins from cancer cell lines. This project focuses on D283 med and U-118mg cell lines which contribute to 12 missing protein identification.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-06-21 | MSV000087678 | MassIVE
ProteomicsThe exploration of Missing Proteins by a combination approach to enrich the low abundance membrane proteins from several cancer cell lines
Our goal is the identification of more and more the missing proteins from cancer cell lines. This project focuses on the membrance proteins separated by the ultracentrifuge and the low abundant peptides enriched by the Proteominer Kit and the hydrophobic peptides extracted by the organic solvent Ace...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-10-26 | MSV000086369 | MassIVE
ProteomicsEvaluation and minimization of nonspecific tryptic cleavages in proteomic sample preparation
Dataset for evaluation of nonspecific cleavages and artificial modifications using E.coli and A549 cells
ORGANISM(S): Homo Sapiens Escherichia Coli 
2020-01-19 | PXD017186 |
Proteomicsphotoactivation-dependent proximity labeling (PDPL) MS
we report a photoactivation-dependent proximity labeling (PDPL) method designed by genetically attaching photosensitizer protein miniSOG to a protein of interest (POI). Triggered by blue light, singlet oxygen is generated, enabling temporally-resolved chemical probe labeling.
ORGANISM(S): Homo Sapiens 
2022-06-22 | PXD034811 |
ProteomicsProbing the Role of O-GlcNAcylation in Modulating Protein-DNA Interactions: Insights from a Proteomic Transcription Factor Response Element-Based Pulldown Screening Approach
O-linked β-N-acetylglucosamine (O-GlcNAc), a critical post-translational modification (PTM) predominantly found in the nucleus, plays a substantial role in regulating gene expression by modulating transcription factors (TFs) activity. Herein, by utilizing a pulldown screening approach termed as tand...
ORGANISM(S): Homo Sapiens 
PXD057128 |
ProteomicsO-GlcNAcylation elevates topoisomerase IIα catalytic activity: a role in the chemotherapy resistance of breast cancer
DNA topoisomerase IIα (TOP2A) plays a vital role in replication and cell division by catalytically altering DNA topology. It is a prominent target for anticancer drugs. However, it is currently unknown whether TOP2A is O-GlcNAc-modified, and the mechanism by which interplay between TOP2A and O-GlcNA...
ORGANISM(S): Homo Sapiens 
PXD041284 |
MetabolomicsTranscriptomic dynamics control rapid transition of core crop functions in 'lactating' pigeon

Pigeons (Columba livia) are widely kept as domesticated pets worldwide, and may have adapted to captivity through the evolutionarily specialized ability to produce ‘milk’ in the crops of both male and female parents via rapid proliferation and shedding of lipid- and protein-enriched epithelial ce...

2023-02-13 | MTBLS5195 | MetaboLights
UnknownCavity-altered superconductivity.
Not available
S-EPMC12935536 | biostudies-literature
UnknownCharacterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells.
Not available
S-EPMC8904132 | biostudies-literature
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