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TranscriptomicsThe histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
Recent studies have identified a Lys 27-to-methionine (K27M) mutation at one allele of H3F3A, one of the two genes encoding histone H3 variant H3.3, in 60% of high-grade pediatric glioma cases. The median survival of this group of patients after diagnosis is ∼1 yr. Here we show that the levels of H3...
ORGANISM(S): Homo sapiens 
2014-09-20 | E-GEOD-61586 | biostudies-arrayexpress
UnknownDraft genome of the leopard gecko, Eublepharis macularius.
Not available
S-EPMC5080775 | biostudies-literature
ProteomicsIntegrative proteomic and phosphoproteomic profiling of testis from Wip1-knockout mice: insights into mechanisms of reduced fertility
Spermatogenesis plays an important role in the mammalian testis, involving in the complex processes of mitosis, meiosis, and spermiogenesis. Spermatogenesis may also be disrupted in the absence of the immunological and ‘fence’ functions of the BTB, resulting in male subfertility or infertility. Mice...
ORGANISM(S): Mus musculus (Mouse) 
2018-11-02 | PXD009220 | Pride
Fertility Proteomic Phosphoproteomic Knockout mice Testis Wip1 
UnknownLandmine Press Kinematics Measured with an Enhanced YOLOv8 Model and Mathematical Modeling
Not available
S-EPMC12944738 | biostudies-literature
UnknownLongissimus Dorsi Muscle Transcriptomic Analysis of Simmental and Chinese Native Cattle Differing in Meat Quality.
Not available
S-EPMC7770222 | biostudies-literature
ProteomicsMouse epididymis LC-MSMS - Male Fertility Potential Molecular Mechanisms Revealed by iTRAQ-Based Quantitative Proteomic Analysis of the Epididymis from Wip1-/- Mice
The wild-type p53-induced phosphatase 1 (WIP1) frustrated mice exhibited defects in reproductive organs. This study aimed to understand how Wip1 deficiency affects the spermatogenesis or maturation. We employed the Wip1-/- mouse model and conducted a gel-free iTRAQ LC-MS/MS based quantitative proteo...
ORGANISM(S): Mus musculus (Mouse) 
2019-01-16 | PXD010125 | Pride
Lc-msms Mouse Sperm Itraq Epididymis 
ProteomicsEvolutionary collateral sensitivity to pleuromutilins in vancomycin-resistant Enterococcus faecium
The rise of antibiotic resistance and decline of antibiotic discovery urgently calls for novel mechanistic understanding of pharmacological and evolutionary interactions between antibiotics and multidrug resistant bacteria to revitalize existing antibiotics. The evolutionary cross-resistance to anti...
ORGANISM(S): Enterococcus faecalis (Streptococcus faecalis) 
2022-05-20 | PXD030906 | Pride
Collateral sensitivity，vancomycin-resistant enterococcus faecium，pleuromutilin 
UnknownGenome-wide identification of DUF506 gene family in Oryzasativa and expression profiling under abiotic stresses.
Not available
S-EPMC10544316 | biostudies-literature
UnknownA novel nomogram and prognostic factor for metastatic renal cell carcinoma survival in the era of immune checkpoint inhibitors (ICIs).
Not available
S-EPMC9846485 | biostudies-literature
UnknownOff-tumor targets compromise antiangiogenic drug sensitivity by inducing kidney erythropoietin production.
Not available
S-EPMC5692529 | biostudies-literature
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