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MetabolomicsContributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer

BACKGROUND Increasing evidence implicates microbiome involvement in the development and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of gut or oral microbiota can lead to colonization in the pancreas, resulting in dysbiosis that culminates ...

2023-08-09 | MTBLS7260 | MetaboLights
TranscriptomicsDICER- andM-BM- AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation (RNA-seq)
Although liganded nuclear receptors have been established to regulate RNA polymerase II (Pol II)-dependent transcription units, their role in regulating Pol III-transcribed DNA repeats remains largely unknown. Here we report that ~2-3% of the ~100,000-200,000 total human DR2 Alu repeats located in p...
ORGANISM(S): Homo sapiens 
2012-12-29 | E-GEOD-42563 | biostudies-arrayexpress
MetabolomicsHost: Microbiome co-metabolic processing of dietary polyphenols – An acute, single blinded, cross-over study with different doses of apple polyphenols in healthy subjects
Apples are one of the most commonly consumed fruits and their high polyphenol content is considered one of the most important determinants of their health-promoting activities. Here we studied the nutrikinetics of apple polyphenols by UHPLC-HRMS metabolite fingerprinting, comparing the bioavailabili...
2018-10-11 | MTBLS473 | MetaboLights
UnknownIntegrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3.
Not available
S-EPMC8096432 | biostudies-literature
UnknownSmectic phase in suspensions of gapped DNA duplexes.
Not available
S-EPMC5116068 | biostudies-literature
UnknownGraphene oxide/reduced graphene oxide films as protective barriers on lead against differential aeration corrosion induced by water drops.
Not available
S-EPMC9419162 | biostudies-literature
ProteomicsIn Situ Visualization of TACO1-Mediated Efficient Mitochondrial Translation Elongation
Isolation of CO1 mRNA ribonucleoprotein complexes from TACO1 KO and WT HEK293T cells
ORGANISM(S): Homo sapiens (Human) 
2026-01-02 | PXD064026 | Pride
Human Taco1 Mitoribosome Co1 Translation 
UnknownPME10 Is a Pectin Methylesterase Driving PME Activity and Immunity Against Botrytis cinerea in Grapevine (Vitis vinifera L.).
Not available
S-EPMC12576464 | biostudies-literature
TranscriptomicsAge-related changes in microRNA levels in serum (mRNA)
Age-related changes in microRNA levels in serum 20 nM biotinylated miRIDIAN miR-1248 mimic (Thermo Scientific) or a negative control, biotinylated miRIDIAN C. elegans miR-67 (here named Con-miR) using Lipofectamine 2000. Forty eight hours post transfection, total RNA was isolated using the mirVana...
ORGANISM(S): Homo sapiens 
2013-10-09 | E-GEOD-51309 | biostudies-arrayexpress
TranscriptomicsAge-related changes in microRNA levels in serum
microRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate gene expression by targeting specific mRNAs. Altered expression of circulating miRNAs have been associated with age-related diseases including cancer and cardiovascular disease. Although we and others have found an age-...
ORGANISM(S): Homo sapiens 
2013-12-18 | E-GEOD-53439 | biostudies-arrayexpress
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