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UnknownRisk factor differences in five-year progression of Intracranial artery stenosis and cerebral small vessel disease in general population.
Not available
S-EPMC11378397 | biostudies-literature
ProteomicsLipids associated with plant systemic acquired resistance, identified by metabolomics approach in an Arabidopsis thaliana model
Background. Systemic acquired resistance (SAR) in plants protects against a wide variety of pathogens. Numerous studies in recent decades have focused on induction of SAR, but its molecular mechanism remains largely unknown. Methods. We used a metabolomics approach based on ultra-high-performance l...
ORGANISM(S): Arabidopsis Thaliana 
2021-08-18 | PXD027990 |
ProteomicsSpatial-region-resolved proteomic map reveals mechanism of COVID-19-associated heart injury
Coronavirus disease 2019 (COVID-19) induces diverse clinical manifestations accompanied by multi-organ dysfunction. Of these, heart complications are the most life threatening. Direct myocardial and vascular injuries due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) drive systemic ...
ORGANISM(S): Homo Sapiens 
2022-01-26 | PXD031249 |
ProteomicsLow-dose metformin targets the lysosome-AMPK pathway through PEN2
Metformin is the most prescribed anti-diabetic medicine, and has also been shown to have other various benefits, such as anti-aging and anti-cancer effects. For clinical doses of metformin, it is known that AMPK plays a major role; however, the direct molecular target of metformin remains unclear. H...
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-12-01 | PXD030090 |
ProteomicsAMPK targets PDZD8 to promote carbon source shift to glutamine
This project contains the raw MS data that identified PDZD8 as a substrate of AMPK on the MAM of ER-mitochondria contact. They also revealed that site T527 is an AMPK-phosphorylation site.
ORGANISM(S): Mus Musculus 
PXD041428 |
UnknownImplicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Not available
S-EPMC9793579 | biostudies-literature
UnknownA multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Not available
S-EPMC9388392 | biostudies-literature
UnknownThe power of genetic diversity in genome-wide association studies of lipids.
Not available
S-EPMC8730582 | biostudies-literature
UnknownThe trans-ancestral genomic architecture of glycemic traits.
Not available
S-EPMC7610958 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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