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TranscriptomicsmRNA-seq data from embryonic autopods of the common bent-wing bat (Miniopterus schreibersii)
The only freely flying mammals, bats, develop a pair of dramatically elongated hands and broad wing membranes. It is hypothesized that alterations of many gene expressions result in the bat wing formation. However, it remains to be proved. Here, by mRNA-seq, we found that hundreds of genes are signi...
ORGANISM(S): Miniopterus schreibersii 
2014-04-14 | E-GEOD-50699 | biostudies-arrayexpress
ProteomicsMettl1-mediated B cell responses
Germinal center (GC) response requires increased protein synthesis. We identify the methyltransferase METTL1 as a translational checkpoint during GC responses. Therefore, we immunized mettl1-cko mice and control mice with NP-OVA, and sorted spleen B cells on day 14.
ORGANISM(S): Mus musculus (Mouse) 
2024-11-01 | PXD057426 | Pride
Mice B cells Spleen 
TranscriptomicsDigital gene expression tag profiling of digit morphologies in bats
As the only truly flying mammals, bats use their unique wing formed from elongated digits connected by membranes to power their flight. The forelimb of bats consists of four elongated digits (digits II-V) and one shorter digit (digit I) that is morphologically similar to the hindlimb digits. Elongat...
ORGANISM(S): Myotis ricketti 
2010-12-06 | E-GEOD-20038 | biostudies-arrayexpress
TranscriptomicsDelineation of diverse macrophage activation programs in response to intracellular parasites and cytokines
To provide a global perspective on the relationships between macrophage activation programs and to understand how certain pathogens circumvent them, we used transcriptional profiling by genome wide microarray analysis to compare the responses of mouse macrophages following exposure to the intracellu...
ORGANISM(S): Mus musculus 
2010-04-13 | E-GEOD-20087 | biostudies-arrayexpress
TranscriptomicsIn-depth analysis of microRNA in bat hibernating regulation
We report the application of the Illumina/Solexa sequencing-by-synthesis platform to identify microRNA, which invovled in bat hibernating regualtion, in brain and adipose tissue. Total 866 microRNAs (including 477 novels) were identified and 269 microRNAs showed significant expression differences du...
ORGANISM(S): Myotis ricketti 
2015-12-31 | E-GEOD-29053 | biostudies-arrayexpress
ProteomicsLC/MS Data for Human CD4+ T cells
For metabolic profiling of human CD4+ T cells，stable isotope labeling (SIL) and metabolomics SIL experiments were performed with in vitro-activated T cells using liquid chromatography (LC) coupled to mass spectrometry (MS).
ORGANISM(S): Homo Sapiens 
PXD055329 |
ProteomicsGC/MS data for mouse spleen CD4+ T cells
For metabolic profiling of mouse CD4+ T cells, stable isotope labeling (SIL) experiments were performed with in vitro-activated T cells using gas chromatography (GC) coupled to mass spectrometry (MS).
ORGANISM(S): Mus Musculus 
PXD055328 |
ProteomicsEcN OMVs mass spectrometry proteomics data
The mass spectrometry proteomics data of outer membrane vesicles of wide-type Escherichia coli Nissle 1917 and engineered Escherichia coli Nissle 1917
ORGANISM(S): Escherichia Coli 
PXD053377 |
ProteomicsPhosphoproteomic in soleus and biceps femoris muscle
We used phosphoproteomic profiling of slow-twitch (soleus, SOL) and fast-twitch (biceps femoris, BF) muscle to identify differences between these muscle types.
ORGANISM(S): Sus Scrofa Domesticus 
2022-08-16 | PXD036066 |
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