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ProteomicsLong noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity-proteome
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity
ORGANISM(S): Homo Sapiens 
2022-12-28 | PXD039107 |
ProteomicsSystematic investigation into the dynamic alterations in the proteome and phosphoproteome of mycobacteria following overexpression of PknG
Systematic investigation into the dynamic alterations in the proteome and phosphoproteome of mycobacteria following overexpression of PknG
ORGANISM(S): Mycolicibacterium Smegmatis Mc2 51 
PXD063872 |
ProteomicsQuantitative Pattern of hPTMs by Mass Spectrometry-based Proteomics with Implications for Triple-Negative Breast Cancer
Triple-negative breast cancer (TNBC) is characterized by its aggressive behavior, with trend to early relapse and metastasis as well as poor survival. Limited therapies and lack of effective therapeutic targets are one of the main challenges in clinical management of TNBC. Histone post-translationa...
ORGANISM(S): Homo Sapiens 
2024-02-01 | PXD049101 |
ProteomicsSubcommissural organ (SCO) contributes to brain development via SCO-secreted peptides
To explore the role of SCO and its functional mechanism, we measure the SCO-derived peptide in CSF from C57B/6 mice and SCO-ablated mice.
ORGANISM(S): Mus Musculus 
2025-02-04 | PXD040641 |
MetabolomicsExploring the gut microbiome and serum metabolome interplay in non-functioning pituitary neuroendocrine tumors.

The gut microbiome has emerged as a potential factor in cancer pathogenesis, but its role in non-functioning pituitary neuroendocrine tumors (NF-PitNETs) remains unclear. This study aimed to elucidate gut microbiome and metabolomic alterations in NF-PitNETs by comparing microbial diversity, patho...

2025-06-16 | MTBLS12328 | MetaboLights
Proteomicsmetabolic reprogramming induced by LONP1 in prostate cancer is closely coupled with disease progression
To understand how Lon protease 1(Lonp1) knockin promotes prostate cancer metastasis in vivo, we performed proteomic analysis on prostates extracted from 40-week-old wild-type (WT), Lonp1KI, Pten-/- and Pten-/-; Lonp1KI mice.
ORGANISM(S): Mus Musculus 
PXD053059 |
ProteomicsER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ORGANISM(S): Homo Sapiens 
PXD055020 |
ProteomicsProteomic analysis of linear ubiquitination substrates based on NAEK-Ub probe in live cells
While linear ubiquitin plays critical roles in multiple cell signaling pathways, few substrates have been identified. Global profiling of linear ubiquitin substrates represents a significant challenge because of the low endogenous level of linear ubiquitination, the none-specific binding of linear p...
ORGANISM(S): Homo Sapiens 
2022-02-11 | PXD031600 |
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