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We investigated genome-wide nucleosome coverage and histone methylation occupancies in somatic MEFs, intermediate pre-iPSCs and fully reprogrammed iPSCs. We found that nucleosome occupancies increased in promoter regions and decreased in intergenic regions in pre-iPSCs and then recover to an interme...
ORGANISM(S): Mus musculus 
PBDEs are widely used in consumer and household products as flame retardants. Many studies have shown that PBDEs could disrupt thyroid hormone homeostasis and adversely affect brain development. Here, we explored the toxical effects of BDE209 on HEK 293 cells and found that BDE209 may have a role in...
ORGANISM(S): Homo sapiens 
Eight-week-old mice were divided into six groups: sham group, 10min after MI, 1h after MI, 6h after MI, 24h after MI and 72h after MI. Myocardial infarction was performed by ligating the proximal left anterior descending coronary artery. Then the infarction myocardial tissue was taken for DIA protei...
ORGANISM(S): Mus Musculus 
2020-07-05 | PXD020193 |
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