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ProteomicsInvestigation of the Dynamical Expression of Nostoc flagelliforme Proteome in Response to Rehydration
In this study, LC-MS/MS combined with isobaric chemical labeling technique (iTRAQ) was used to quantify dynamic changes of proteins in N. flagelliforme during the rehydration processes. Approximately 113 proteins were identified to be differentially expressed in photosynthesis, defense response, bios...
ORGANISM(S): Nostoc Flagelliforme Str. Sunitezuoqi 
2019-11-28 | PXD010464 |
ProteomicsEffects of swimming exercise on the urinary proteome in rats
In this study, the experimental rats were administered a 7-week swimming training (5 days per week, 40 min/day). To identify changes in the urinary proteome during regular swimming exercise, urine samples were collected at week 2, 5, and 7. Urine proteins were identified by liquid chromatography cou...
ORGANISM(S): Rattus Rattus 
2021-05-06 | PXD025814 |
ProteomicsHIRA and dPCIF1 coordinately establish totipotent chromatin and control orderly ZGA in Drosophila embryos
In order to understand the molecular mechanism underlying the action of dPCIF1 in early embryos, we carried out co-immunoprecipitation (co-IP) assays followed by mass spectroscopic analysis using dPCIF1GFP-KI early embryos (0.5–1.5 hours). In this assay, we identified a large number of dPCIF1-intera...
ORGANISM(S): Drosophila Melanogaster 
2024-01-18 | PXD048659 |
ProteomicsMapping novel biomarkers of liver injury by tissue proteomic analysis
Liver damage is a dynamic process and evaluation of liver injury degree is the key step in disease diagnose. However, few common markers between different types of liver injury have been reported. Herein, we generate three liver injury mouse models including Con A induced, CCl4 injected and subjecte...
ORGANISM(S): Mus Musculus 
2020-11-25 | PXD022716 |
ProteomicsTMT proteomics analysis of cerebrospinal fluid from patients with cerebral venous sinus thrombosis
In the present study, we detected the alterations of the CSF protein spectrum of CVST patients by TMT technique, screen differentially expressed proteins, analyze the functions of these signals through bioinformatics methods, and finally validate the key molecules through parallel reaction monitorin...
ORGANISM(S): Homo Sapiens 
2022-11-22 | PXD038259 |
Proteomics10-HDA reduces the hydroxyl free radical-induced damage to vascular smooth muscle cells by rescuing protein and energy metabolisms
10-hydroxydec-2-enoic acid (10-HDA), a natural agent from royal jelly, could fight against cell and tissue damage, yet the underlying mechanisms are still unexplored. Here, we found the scavenging rate of hydroxyl free radical (•OH) by 2% (g/mL) 10-HDA was more than 20%, which was achieved by a mult...
ORGANISM(S): Mus Musculus 
2021-11-22 | PXD029873 |
ProteomicsMulberry leaf ameliorate STZ induced diabetic rat by regulating hepatic glycometabolism and fatty acid β-oxidation
Mulberry leaf ameliorate STZ induced diabetic rat by regulating hepatic glycometabolism and fatty acid β-oxidation
ORGANISM(S): Rattus Rattus 
2024-10-29 | PXD057279 |
ProteomicsProteomic stratification of prognosis and treatment options for small cell lung cancer
We analyzed surgically resected formalin-fixed, paraffin-embedded (FFPE) SCLC samples by proteomic profiling and stratified SCLC into three subtypes (S-I, S-II, and S-III) with distinct clinical outcomes and chemotherapy responses.
ORGANISM(S): Homo Sapiens 
2025-05-27 | PXD064316 |
ProteomicsProteomic analysis of Hypsibius henanensis sp.nov. suffered from 12C6+ heavy ion radiation based on label-free technology
Tardigrades are a kind of species that can tolerate ultra-high doses of ionizing radiation. Here, we used heavy ions at different doses of 0,200 and 2000Gy to irradiate Hypsibius henanensis sp.nov.. Label-free proteomic identification was performed on the samples, each dose containing 3 repetitions
ORGANISM(S): Tardigrada 
2023-09-20 | PXD045537 |
ProteomicsDetection of betalains from the extracts of H. henanensis sp. nov.
Identification of betalains from the extracts of H. henanensis sp. nov. using untargeted metabolomics.
ORGANISM(S): Tardigrada 
2024-03-22 | PXD050882 |
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