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ProteomicsPhosphorylation of SMURF2 by ATM exerts a negative feedback control of DNA damage response
Timely repair of DNA double-strand breaks (DSBs) is essential to maintaining genomic integrity and preventing illnesses induced by genetic abnormalities. We previously demonstrated that the E3 ubiquitin ligase Smad ubiquitin regulatory factor 2 (SMURF2) plays a critical tumor suppressing role via i...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-10-26 | PXD021420 | Pride
Smurf2 Atm Phosphorylation Dna damage response 
UnknownNut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance).
Not available
S-EPMC5891130 | biostudies-literature
UnknownStudy on the enhancement of low carbon-to-nitrogen ratio urban wastewater pollutant removal efficiency by adding sulfur electron acceptors.
Not available
S-EPMC11500869 | biostudies-literature
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
UnknownSynergistic regenerative therapy of thin endometrium by human placenta-derived mesenchymal stem cells encapsulated within hyaluronic acid hydrogels.
Not available
S-EPMC8822809 | biostudies-literature
UnknownApelin enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly through Wnt/β-catenin signaling pathway.
Not available
S-EPMC6593611 | biostudies-literature
ProteomicsCardiac proteomics in diabetic cardiomyopathy mice treated with GLP-1 receptor agonist
the changes of cardiac proteomics in diabetic cardiomyopathy mice treated with GLP-1 receptor agonist
ORGANISM(S): Mus Musculus 
2021-09-10 | PXD028452 |
MetabolomicsDT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates

Nonalcoholic steatohepatitis (NASH) prevalence is rising with no pharmacotherapy approved. A major hurdle in NASH drug development is the poor translatability of preclinical studies to safe/effective clinical outcomes, and recent failures highlight a need to identify new targetable pathways. Dysr...

2023-04-13 | MTBLS5005 | MetaboLights
UnknownDeep learning on tertiary lymphoid structures in hematoxylin-eosin predicts cancer prognosis and immunotherapy response.
Not available
S-EPMC10959936 | biostudies-literature
UnknownPES1 is a critical component of telomerase assembly and regulates cellular senescence.
Not available
S-EPMC6520020 | biostudies-literature
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