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UnknownMethylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer susceptibility.
Not available
S-EPMC4145786 | biostudies-literature
MetabolomicsFatty acid oxidation protects cancer cells from apoptosis through increasing mitochondrial membrane lipids

Overcoming resistance to chemotherapies remains a major unmet need for cancers such as triple negative breast cancer (TNBC). Therefore, mechanistic studies to provide insight for drug development are urgently needed to overcome TNBC therapy resistance. Recently, an important role of fatty acid β-...

2022-05-31 | MTBLS4709 | MetaboLights
UnknownLendenfeldaranes W-Y, new 24-homoscalaranes from a marine sponge <i>Lendenfeldia</i> species.
Not available
S-EPMC12624399 | biostudies-literature
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
ProteomicsMEST Promotes Lung Cancer Invasion and Metastasis by Interacting with VCP to Activate NF-κB Signaling
Active cell invasion is a hallmark of metastatic cancer, leading to unfavorable clinical outcome. We here established high-invasive lung cancer cell models, A549-i8 and H1299-i8, and identified mesoderm-specific transcript (MEST) as a novel invasive regulator for lung cancer. MEST overexpression pro...
ORGANISM(S): Homo Sapiens 
2021-06-02 | PXD026409 |
ProteomicsEpigenetic regulation of fruit shape determination by JAGGED gene in Capsella rubella
transcription factor CrJAG interacts with histone chaperones to maintain chromatin accessibility and expression of cell cycle-related genes, thereby controlling fruit shape determination in Capsella.
ORGANISM(S): Capsella Rubella 
2026-04-25 | PXD077639 |
ProteomicsThe novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L
Here, by state-of-the-art mass spectrometry-based quantitative proteomic technology, we systematically screened the potential neo-substrates of a novel thalidomide derived cereblon modulator CC-885.
ORGANISM(S): Homo Sapiens 
2020-01-11 | PXD017071 |
ProteomicsGel-based LC-MSMS, the interactome of XAF1 in 293T cells
We utilized mass spectrometry to analyze the interacting proteins of XAF1 in 293T cells.
ORGANISM(S): Homo Sapiens 
2023-03-22 | PXD041021 |
ProteomicsGel-based LC-MSMS, the interactome of RNF114 in 293T cells
We utilized mass spectrometry to analyze the interactome of RNF114 in 293T cells.
ORGANISM(S): Homo Sapiens 
2023-08-07 | PXD044440 |
ProteomicsSpatial-region-resolved proteomic map reveals mechanism of COVID-19-associated heart injury
Coronavirus disease 2019 (COVID-19) induces diverse clinical manifestations accompanied by multi-organ dysfunction. Of these, heart complications are the most life threatening. Direct myocardial and vascular injuries due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) drive systemic ...
ORGANISM(S): Homo Sapiens 
2022-01-26 | PXD031249 |
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