Sort   by:  
 Page size 
ProteomicsDLX2-FLAG IP-MS in embryonic bodies (EBs): Protein complexes identification
The ectomesenchyme generates much of the craniofacial skeleton, sutures, and diverse connective tissues in the mammalian head, yet its derivation from embryonic stem cells (ESCs) and the underlying molecular drivers remain poorly defined. Here, we identified Dlx2 as a key regulator that efficiently ...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-06 | PXD064236 | Pride
Embryonic bodies Ip-ms Dlx2-flag 
ProteomicsIdentification of Sh3rf3-interacting proteins in mouse prefrontal cortex by immunoprecipitation mass spectrometry
Sh3rf3 is an ASD-associated gene,Sh3rf3 deficiency reduces excitatory synaptic strength in prefrontal cortex and decreases the readily releasable vesicle pool and attenuated vesicle replenishment.To delve into the underlying mechanisms for impaired excitatory transmission, we performed immunoprecipi...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-23 | PXD061685 | Pride
Prefrontal cortex Mouse Ip-ms Sh3rf3 
UnknownElucidating the origins of multimode vibrational coherences of polyatomic molecules induced by intense laser fields.
Not available
S-EPMC5622070 | biostudies-literature
ProteomicsQuantitative proteomic and phosphoproteomic profiling of Sh3rf3-deficient ASD mouse model via 6Plex-TMT and phosphoproteomic
This study aims to systematically investigate the molecular mechanisms underlying autism spectrum disorder (ASD) by analyzing the proteome and phosphoproteome of a Sh3rf3-deficient mouse model. SH3RF3 (SH3 domain-containing RING finger protein 3) is implicated in synaptic regulation pathways, yet it...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-23 | PXD061722 | Pride
Prefrontal cortex Mouse Ms Sh3rf3 
ProteomicsFunctional identification of protocadherin alpha 9 (PCDHA9) as a candidate causative gene for amyotrophic lateral sclerosis
Mice were sacrificed after anesthesia by isoflurane following neck cutting. The spinal cord L3-L5 was taken and frozen in liquid nitrogen immediately and the ventral horn of the bilateral spinal cord (about 400um thick in gray matter area) was collected at low temperature. The samples were digested ...
ORGANISM(S): Mus Musculus 
2023-06-12 | PXD042929 |
ProteomicsTransfer of the high-quality sugar metabolic model of Aspergillus niger is reliable within the same fungal phylum, but limited for fungi of other phyla
Validation of metabolic models, extrapolated from the reference sugar catabolism genetic network of Aspergillus niger by using an orthology-based approach, of evolutionarily diverse fungi.
ORGANISM(S): Trichoderma Reesei (ncbitaxon:51453) Penicillium Subrubescens (ncbitaxon:1316194) Aspergillus Niger (ncbitaxon:5061) Phanerochaete Chrysosporium Rp-78 (ncbitaxon:273507) Aspergillus Nidulans (ncbitaxon:162425) 
MSV000090441 | MassIVE
ProteomicsIP-MS of SpvB and SopD2, four biological replicates in 18 LC-MS/MS experiments.
To screen the host targets of SpvB, we performed IP-MS analyses and measured four biological replicates of paired SpvB and SopD2 samples in 18 LC-MS/MS experiments.
ORGANISM(S): Homo Sapiens 
2023-07-25 | PXD044057 |
ProteomicsDeubiquitinase OTULIN dampens RIG-I dependent type I IFN signaling by removing the linear ubiquitination from TRAF6
In this study, we observed a global increase in intracellular linear ubiquitination upon RNA viral infection, suggesting that linear ubiquitination may be a prerequisite for the initiation of antiviral innate immunity. Furthermore, using a combination of various cell lines and in vivo experiments, w...
ORGANISM(S): Homo Sapiens 
2025-11-15 | PXD070809 |
ProteomicsDevelopment of Substrate-Directed Activity-Based Probes via Disulfide-Trapping for Site-Specific Interrogation of Nucleosomal Deubiquitination
Activity-based ubiquitin probes (Ub-ABPs) have been instrumental in interrogating deubiquitinases (DUBs), yet conventional Ub-ABPs lack the substrate-specific and site-specific contextual cues required to investigate nucleosomal DUBs, whose activity is tightly regulated by the chromatin environments...
ORGANISM(S): Homo Sapiens 
2025-12-30 | PXD072417 |
ProteomicsShigella flexneri evades septin-mediated cell-autonomous immunity via protein ADP-riboxanation
We demonstrate that OspC effectors enable S. flexneri to evade septin cage entrapment. Mechanistically, OspC catalyzes ADP-riboxanation of SEPT9 at Arg561, a critical site essential for stabilizing septin hetero-oligomers. Notably, ADP-riboxanation or mutation of Arg561 impairs septin polymerization...
ORGANISM(S): Homo Sapiens 
2025-11-04 | PXD070327 |
Sort   by:  
 Page size