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ProteomicsDNAJB9 promotes epithelial-mesenchymal transition in the nasal epithelium of chronic rhinosinusitis by enhancing TRIM22-mediated IκBα degradation
This study investigates the functional role of DNAJB9 in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). Using quantitative proteomics alongside human tissue analysis and murine models, we found that DNAJB9 is significantly upregulated in CRSwNP nasal epithelium and closely mi...
ORGANISM(S): Homo sapiens (Human) 
2026-06-17 | PXD079333 | Pride
Chronic sinusitis  epithelial-mesenchymal transition  dnajb9  ubiquitination  nf-κb 
UnknownCumulative Ecological Impact of Cascade Hydropower Development on Fish Community Structure in the Main Stream of the Xijiang River, China.
Not available
S-EPMC11851437 | biostudies-literature
UnknownEnhancement mechanisms of short-time aerobic digestion for waste activated sludge in the presence of cocoamidopropyl betaine.
Not available
S-EPMC5647449 | biostudies-literature
ProteomicsGlycoproteomics revealed novel N-glycosylation biomarkers for early diagnosis of lung adenocarcinoma cancers
Circulating biomarkers play important roles in diagnosis of malignant tumors. N-glycosylation is an important post-translation patter and obviously affect biological behaviors of malignant tumor cells. However, the role of N-glycosylation sites in early diagnosis of tumors still remains further inve...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036198 | Pride
Lung adenocarcinoma  early diagnosis  circulating biomarkers  n-glycosylation  machine learning. 
ProteomicsHuman cancer cell MCF-7 IP-PTEN MS
The MCF-7 cells were lysed using RIPA lysis buffer with a high salinity content to break out non-covalent binding of proteins. Then IP under partially denaturing conditions was performed and demonstrated that anti-PTEN precipitates were detected as smear bands, then mass spectrometry analysis of the...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD021544 | Pride
Human Breast cancer Pten Ms 
ProteomicsBbubalis - Sperm, SC (Fuetal,theriogenology.2019)
abundance based on Spectral counting, Interaction consistency score: 9.5, Coverage: 12
ORGANISM(S): 89462 
2019-00-00 | 562539239 | PAXDB
ProteomicsMCF-7 PTEN-Nedd8 IP-MS
We intended to elucidate the underlying mechanism of PTEN-Nedd8 in tumorigenesis. So, we firstly employed affinity purification and mass spectrometry to interrogate PTEN-Nedd8 interactome in nucleus.
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD011395 | Pride
Human Breast cancer cell Nedd8 Pten Ip-ms 
ProteomicsMCF-7 Flag-need8 IP-MS
To allow the proteomic identification of proteins modified with Nedd8, we firstly employed affinity purification and mass spectrometry to interrogate Nedd8 interactome.
ORGANISM(S): Homo sapiens (Human) 
2022-04-01 | PXD011368 | Pride
Human Breast cancer cell Ip-ms Mcf-7 
MetabolomicsNMR- and LC–MS/MS-based urine metabolomic investigation of the subacute effects of hexabromocyclododecane in mice (NMR assay)
In the present study, both untargeted and targeted metabolomics approaches were used to evaluate the subacute effects of hexabromocyclododecane (HBCD) on mice urine metabolome. Untargeted metabolomics based on 1H NMR showed that HBCD exposure disturbed mice metabolism in both dosed groups, especiall...
2015-02-14 | MTBLS166 | MetaboLights
ProteomicsHs_C-HPP_EnrichmentStrategy_membrane
Enrichment strategy for searching missing protein, HCCLM6 and MHCC97L, membrane and
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005437 | PeptideAtlas
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