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ProteomicsA small-molecule inhibitor targeting AKR1C1 suppresses cell proliferation and metastasis in non-small cell lung cancer
Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-related deaths, characterized by highly invasion and metastasis. Aldo-keto reductase family 1 member C1 (AKR1C1) plays an important role in cancer cell proliferation and metastasis and has gained attention as an anticancer dru...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD031082 | Pride
Alantolactone  akr1c1  anticancer  target identification  non-small cell lung cancer 
UnknownIncreased expression of EZH2 indicates aggressive potential of urothelial carcinoma of the bladder in a Chinese population.
Not available
S-EPMC6290761 | biostudies-literature
ProteomicsAnalyze the post-translation modification of UVRAG
To explore the role of post-translational modification on UVRAG, we used tandem mass spectrometry (MS/MS) to analyze the UVRAG from cells.
ORGANISM(S): Homo Sapiens 
2022-06-14 | PXD034521 |
ProteomicsProteomic Analysis of Human Nucleus Pulposus in Young and Elderly Individuals Using TMT Quantification
This project investigates the differential proteomic profiles of human nucleus pulposus samples from young and elderly individuals. Using Tandem Mass Tag (TMT) quantification, we aim to identify and compare protein expression differences between the two groups. The research explores the biological i...
ORGANISM(S): Homo Sapiens 
2025-06-23 | PXD065307 |
ProteomicsExploring the interaction proteins of Sub1 in aging cardiomyocytes by protein MS
After transferring the Sub1 Flag plasmid into HL-1 cells, the cells were treated with bleomycin for 24 hours, followed by immunoprecipitation using Flag magnetic beads and protein mass spectrometry.
ORGANISM(S): Mus Musculus 
2026-06-24 | PXD080102 |
ProteomicsIdentification of circEZH2_005-interacting proteins by mass spectrometry
liquid chromatography tandem mass spectrometry is used to identificate of the circEZH2_005-Interacting protein pulled down by circEZH2_005 junction probe with protein extracts from Intestinal crypt cells.
ORGANISM(S): Mus Musculus 
2023-03-17 | PXD040925 |
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