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ProteomicsHERC4 suppresses colorectal cancer progression by promoting STAT3 ubiquitination
Our study aims to identify the enzymes that interact with STAT3 and the specific sites where STAT3 undergoes ubiquitination modification.
ORGANISM(S): Homo Sapiens 
2026-03-24 | PXD076133 |
ProteomicsHERC4 suppresses colorectal cancer progression
Our study aims to identify the enzymes that interact with STAT3 and the specific sites where STAT3 undergoes ubiquitination modification.
ORGANISM(S): Homo Sapiens 
2026-04-16 | PXD077280 |
ProteomicsDetection of STAT3 ubiquitination modification sites
Identify all the lysine sites of STAT3 that may be ubiquitinated,The search criteria were as follows: no enzyme was choosed as unspecific; two missed cleavage was allowed; carbamidomethylation (C) were set as the fixed modifications; the oxidation (M) and ubiquitination were set as the variable modi...
ORGANISM(S): Homo Sapiens 
2026-05-07 | PXD078167 |
TranscriptomicsIdentification of response genes upon neuronal activation in mouse cortical neurons
We search for developmental changes specific to humans by examining gene expression profiles in the human, chimpanzee and rhesus macaque prefrontal and cerebellar cortex. In both brain regions, developmental patterns were more evolved in humans than in chimpanzees. The major human specific genes in ...
ORGANISM(S): Mus musculus 
2012-02-02 | E-GEOD-29139 | biostudies-arrayexpress
TranscriptomicsRegulation of gene expression program by Fsp27 in white and brown adipose tissue
Background: Brown and white adipose tissues (BAT and WAT) play critical roles in controlling energy homeostasis and in the development of obesity and diabetes. Fsp27 is expressed in both BAT and WAT and promotes lipid storage and the development of obesity and diabetes. In addition, Fsp27-deficient ...
ORGANISM(S): Mus musculus 
2010-07-07 | E-GEOD-22693 | biostudies-arrayexpress
UnknownDysregulation of Microglial Function Contributes to Neuronal Impairment in Mcoln1a-Deficient Zebrafish.
Not available
S-EPMC6426713 | biostudies-literature
UnknownTripartite-motif family protein 35-28 regulates microglia development by preventing necrotic death of microglial precursors in zebrafish.
Not available
S-EPMC7324517 | biostudies-literature
ProteomicsSIRT3 functions as an eraser of histone H3K9 lactylation to modulate transcription for inhibiting the progression of esophageal cancer
As a novel post-translational modification of histone derived from lactate, lysine lactylation (Kla) links lactate metabolism to epigenetic regulation, playing a role in modulation of gene expression in tumor and immune microenvironment. Evidence so far indicates that HDAC1-3 can catalyze the remova...
ORGANISM(S): Homo Sapiens 
2025-02-27 | PXD061251 |
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