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MetabolomicsChlorogenic acid alters ileal microbiota and metabolites in broilers under immune stress

Immune stress in broilers can cause severe economic losses, chlorogenic acid is an effective plant extract for alleviating immune stress. This study investigates the effect of chlorogenic acid on the intestinal microbiota and metabolites of broilers under immune stress. 312 broilers were randomly...

2025-06-09 | MTBLS11790 | MetaboLights
ProteomicsEvaluation of binding preference of different microtubes for nanoproteomics sample preparation
We explored the protein and peptide loss in conventional microtubes during experiment process. We further investigated the binding preferences of different microtubes by the physical characteristics of protein and peptides, such as isoelectric point, hydrophobicity, length, and charge.
ORGANISM(S): Homo sapiens (Human) 
2022-12-14 | PXD035774 | Pride
Sample loss Nanoproteomics Microtube Non-specific binding 
ProteomicsTitin-dependent transient ventricular defects result in adult atrial arrhythmia and impaired contractility
Atrial fibrillation (AF), the most common arrhythmia, is occasionally associated with cardiac developmental defects, but causal relationships are poorly defined. Importantly, functional compensation for developmental defects may mask increased risk of arrhythmia in adults. Here, we deleted 9 amino a...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2024-08-09 | PXD038300 | Pride
Titin Cardiac potassium channel Atrial fibrillation Zebrafish 
TranscriptomicsRNA-Seq of cKIT+ sorted cells from 16-16.5 week old fetal testes and ovaries and RNA-Seq of TRA-1-60+ H1 hESCs
Generation of research quality, clinically relevant cell types in vitro from human pluripotent stem cells (hPSCs) requires detailed understanding of the equivalent cell types in humans. Here we analyzed 130 human fetal samples at 6-20 weeks of development and identified the stages in which human cKI...
ORGANISM(S): Homo sapiens 
2012-08-03 | E-GEOD-39821 | biostudies-arrayexpress
ProteomicsMass spectrometry of human A549 cells transfected with EBV BRLF1
The immediate-early protein BRLF1 plays important roles in lytic infection of Epstein-Barr virus (EBV), in which it activates lytic viral transcription and replication. However, knowledge of the influence of BRLF1 on cellular gene expression and transcriptional reprogramming during the early lytic c...
ORGANISM(S): Homo Sapiens 
2020-10-13 | PXD021958 |
ProteomicstRNA-m1A Methylation Regulates the Infection of Magnaporthe oryzae by Supporting Ergosterol Biosynthesis
Ergosterols are essential components of fungal plasma membranes. Inhibitors targeting ergosterol biosynthesis (ERG) genes are critical for controlling fungal pathogens, including Magnaporthe oryzae, the fungus that causes rice blast. In this study we show that the Trm6/Trm61 complex catalyzes dynami...
ORGANISM(S): Pyricularia Oryzae 70-15 
2024-06-07 | PXD051352 |
ProteomicsSS18/BAFs regulate chromatin accessibility dynamics during pluripotent-somatic transition
The exit from pluripotency or pluripotent-somatic transition (PST) landmarks an event of mammalian development, and is also a representative cell-fate transition model, but remains largely unresolved. Recently, we reported construction of robust JUN-induced PST completed in one cell cycle and whose ...
ORGANISM(S): Mus Musculus 
2021-10-22 | PXD029277 |
ProteomicsSS18 regulates pluripotent-somatic transition through phase separation
The transition from pluripotent to somatic states marks a critical event in mammalian development, but remains largely unresolved. Here we report the identification of SS18 as a regulator for pluripotent to somatic transition or PST by CRISPR-based whole genome screens. Mechanistically, SS18 forms m...
ORGANISM(S): Mus Musculus 
2021-05-23 | PXD026208 |
UnknownPrediction of human population responses to toxic compounds by a collaborative competition.
Not available
S-EPMC4568441 | biostudies-literature
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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