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Metabolomics2E,4E-decadienoic acid, a novel anti-oomycete agent from co-culture of Bacillus subtilis and Trichoderma asperellum

Phytophthora nicotianae is an oomycete pathogen of global significance threatening many important crops. It is mainly controlled by chemosynthetic fungicides, which endangers ecosystem and human health; thus, there is an urgent need to explore alternatives for these fungicides. In this s...

2022-08-01 | MTBLS5405 | MetaboLights
GenomicsH3K27me3 ChIP-seq experiment in fruitfly testis somatic gonadal cells
In many metazoans, germ cells are separated from somatic lineages early in development and maintain their identity throughout life. Here we show that a Polycomb group (PcG) component, Enhancer of Zeste [E(z)] H3K27me3-specific methyltransferase, maintains germline identity in Drosophila adult testes...
ORGANISM(S): Drosophila melanogaster 
2014-05-02 | E-GEOD-53238 | biostudies-arrayexpress
TranscriptomicsEsophageal keratinocyte invasion after loss of E-cadherin and TGF receptor type II
Esophageal cancer is one of the deadliest cancers as patients present at late stages of disease. Frequent gene alterations include the loss of E-cadherin and TGFb receptor type II. The goal of this study was to establish a model of esophageal cancer by introducing dominant-negative mutants of E-cadh...
ORGANISM(S): Homo sapiens 
2013-11-12 | E-GEOD-19472 | biostudies-arrayexpress
ProteomicsQuantitative label-free proteomic comparison of the omadacycline-induced E. faecium isolates vs initial separation
Quantitative label-free proteomic comparison of the omadacycline-induced E. faecium isolates vs initial separation type.
ORGANISM(S): Enterococcus faecalis (Streptococcus faecalis) 
2022-02-17 | PXD029978 | Pride
Omadacycline E. faecium Label-free proteomic 
TranscriptomicsThe YbjN regulon in Escherichia coli
YbjN, an enterobacteria-specific protein, is a multicopy suppressor of ts9 temperature sensitivity in Escherichia coli. Microarray study revealed that the expression level of ybjN was inversely correlated with the expression of flagellar, fimbrial and acid resistance genes. Over-expression of ybjN ...
ORGANISM(S): Escherichia coli 
2011-10-14 | E-GEOD-28630 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Avian Pathogenic E. coli WT and mutant
RNA-Seq was performed on Avian pathogenic E. coli (APEC) WT and mutant to investigate the pathogenicity of ArcA (Aerobic Respiratory Control), a global regulator important for E. coli’s adaptation from anaerobic to aerobic conditions and control of that bacterium’s enzymatic defenses against ROS.
ORGANISM(S): Escherichia coli K-12 
2017-03-01 | E-MTAB-3396 | biostudies-arrayexpress
Transcriptomicsflagellar regulon studies
This study examined the genes under the control of FlhDC and sigmaF in E. coli. Keywords: wild-type, deletion and overexepression strains Under defined steady-state growth condition, we used two different genetic approaches to alter the modulator concentration in cells; (1) moderately expressing Fl...
ORGANISM(S): Escherichia coli 
2009-05-01 | E-GEOD-5818 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli cultures grown on different carbon sources
The study investigated the effect of different carbon sources on E. coli global gene expression. We grew MG1655 cells aerobically in MOPS minimal medium with either glucose, glycerol, succinate, L-alanine, acetate, or L-proline as the carbon supply. Samples were taken from each culture at mid log ph...
ORGANISM(S): Escherichia coli 
2007-07-19 | E-GEOD-2037 | biostudies-arrayexpress
ProteomicsUrine proteomic analysis of rat e-cigarette model
In the experiment of 11 rats, samples were collected 5 times, and the two-needle technique was repeated.
ORGANISM(S): Rattus Rattus 
2022-11-25 | PXD038350 |
TranscriptomicsSmall molecule inhibitors suppress expression of both type III secretion and amylovoran biosynthesis genes in Erwinia amylovora
Microarray analysis of E. amylovora treated with compounds no. 3 and no. 9 identified a total of 588 significantly differentially expressed genes. Among them, 95 and 78 genes were, respectively, induced and suppressed by both compounds as compared to DMSO control. Majority of T3SS genes in E. amylov...
ORGANISM(S): Erwinia amylovora 
2013-12-24 | E-GEOD-45602 | biostudies-arrayexpress
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