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ProteomicsChanges of Granulation Tissue Protein Mass Spectrometry in Foot Wound of Diabetes Mellitus after Negative Pressure wound therapy
Before and after negative pressure treatment in 3 diabetic foot patients, the granulation tissue of foot ulcer was sampled and analyzed quantitatively by LC-MS /MS method.
ORGANISM(S): Homo Sapiens 
PXD020929 |
ProteomicsProteomics of Vitreous Humor Reveals Upstream Regulators of Proliferative Diabetic Retinopathy
To investigate the key regulators of the disease by comparing the abundance of vitreous proteins between the patients with proliferative diabetic retinopathy (PDR) and the controls with idiopathic epiretinal membrane (iERM).
ORGANISM(S): Homo Sapiens 
2021-07-26 | PXD027556 |
ProteomicsLysine methylome features in EZH2 wild-type and mutant lymphoma cell line
We used EZH2i-targeted hematological malignancies as an examples and focused on molecular characterization of EZH2 Y641 mutant hematological cell lines. We used the proteomic strategies and compared the protein expression level and lysine methylation level (including mono-, di-, and trimethylaiton) ...
ORGANISM(S): Homo Sapiens 
2019-12-17 | PXD016779 |
ProteomicsGlobal profiling of AMG510 modified proteins identified tumor suppressor KEAP1 as an off-target
Here, we presented a streamlined workflow to measure abundant AMG510 modified peptides including that of KRAS/G12C by direct profiling, and a pan-AMG510 antibody peptide IP workflow to profile less abundant AMG510 off-targets.
ORGANISM(S): Homo Sapiens 
2023-01-11 | PXD029449 |
ProteomicsThe Glomerulus Multi-Omics Analysis Provides Deeper Insights into Diabetic Nephropathy
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD), however, the detail mechanisms remain unclear. Here, we integrated the transcriptomics and proteomics profiles of glomeruli isolated from 50 biopsy-proven DN patients and 25 controls to explore the new discoveries unde...
ORGANISM(S): Homo Sapiens 
2023-03-06 | PXD040617 |
ProteomicsA region-resolved mucosa proteome of the human stomach
The human gastric mucosa is the most active and functional layer that carries out food digestion and metabolic processes in physiological conditions and also the main origin of carcinogenesis in gastric cancer. Anatomically, the human stomach is divided into 7 regions with physiological functions, b...
ORGANISM(S): Homo Sapiens 
2018-11-26 | PXD011821 |
ProteomicsSkeletal muscle-secreted DLPC orchestrates systemic energy homeostasis by enhancing adipose browning
Skeletal muscle-secreted DLPC orchestrates systemic energy homeostasis by enhancing adipose browning
ORGANISM(S): Mus Musculus 
PXD046337 |
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