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ProteomicsCRL2ZER1/ZYG11B recognizes small N-terminal residues for degradation
N-degron pathway plays an important role in the protein quality control and maintenance of cellular protein homeostasis. ZER1 and ZYG11B, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2), recognize N-terminal (Nt) glycine degrons and participate in the Nt-myristoylation qualit...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037312 | Pride
N-terminal acetylation Nt-ser Crl2zer1/zyg11b 
UnknownFibroblasts facilitate lymphatic vessel formation in transplanted heart.
Not available
S-EPMC10945330 | biostudies-literature
UnknownCD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models.
Not available
S-EPMC12208345 | biostudies-literature
UnknownInflammation-related genes S100s, RNASE3, and CYBB and risk of leukemic transformation in patients with myelodysplastic syndrome with myelofibrosis.
Not available
S-EPMC8259211 | biostudies-literature
ProteomicsProteomic analysis of carbapenem-resistant Klebsiella pneumoniae exposure to tigecycline and aminoglycosides
Proteomic analysis of carbapenem-resistant Klebsiella pneumoniae exposure to tigecycline and aminoglycosides
ORGANISM(S): Klebsiella Pneumoniae Subsp. Pneumoniae Hs11286 
2022-01-17 | PXD031030 |
ProteomicsArginine methylation of METTL14 promotes RNA N6-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells
m6A is the most abundant modification of mRNA in mammals and plays an important role in human development and disease. METTL14 is a key component of m6A methyltransferase complex. The project showed that its post-translational arginine methylation can regulate the generation of m6A and the endoderm ...
ORGANISM(S): Homo Sapiens 
2021-05-17 | PXD018458 |
Proteomics,MultiomicsCyclin C-CDK3/8/19 kinases play a tumor-suppressive role in vivo
Cyclin C was cloned as a growth-promoting G1 cyclin1,2, and several studies postulated a role for cyclin C in driving cell proliferation3-8 . Moreover, cyclin C, together with its kinase partner, the cyclin-dependent kinase CDK8, is believed to represent an essential component of basal transcrip...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080728 | MassIVE
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