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MetabolomicsAltered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity

Irritable bowel syndrome (IBS) is one of the functional gastrointestinal disorders characterized by chronic and/or recurrent symptoms of abdominal pain and irregular defecation. Changed gut microbiota has been proposed to mediate IBS; however, contradictory results exist, and IBS-specific microbi...

2021-12-01 | MTBLS2774 | MetaboLights
MetabolomicsResearch on the quality markers of antioxidant activity of Kai-Xin-San based on spectrum-effect relationship
Kai-Xin-San (KXS) is one of the classic famous traditional Chinese medicine prescriptions for amnesia, which has been applied for thousands of years. Modern pharmacological research has found that KXS has significant therapeutic efficacy on nervous system diseases, which is related to its antioxidan...
2023-12-21 | MTBLS8806 | MetaboLights
UnknownComparative Study of the Chemical Constituents and Bioactivities of the Extracts from Fruits, Leaves and Root Barks of Lycium barbarum.
Not available
S-EPMC6514792 | biostudies-literature
UnknownTrio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits.
Not available
S-EPMC6436967 | biostudies-literature
ProteomicsSCN Proteomic Study:electroacupuncture induced circadian control in Suprachiasmatic Nucleus
Recent reports highlight phosphorylation as a major role in the regulation of sleep-wake cycles, to a lesser extent, the phosphoproteome in Suprachiasmatic Nucleus (SCN) is not well understood. We use multiplex tandem mass tag (TMT) - labelling coupled with liquid chromatography-mass spectrometry (L...
ORGANISM(S): Mus Musculus 
2021-10-31 | PXD029450 |
ProteomicsMetabolomics analysis of Rivaroxaban
In this study, plasma metabolomes before and 3 hours after rivaroxaban intake in nonvalvular atrial ûbrillation (NVAF) patients and age/gender-matched controls were analyzed by liquid chromatography coupled with mass spectrometry (LC3MS/MS).
ORGANISM(S): Homo Sapiens 
2022-07-24 | PXD032247 |
ProteomicsLysine methylome features in EZH2 wild-type and mutant lymphoma cell line
We used EZH2i-targeted hematological malignancies as an examples and focused on molecular characterization of EZH2 Y641 mutant hematological cell lines. We used the proteomic strategies and compared the protein expression level and lysine methylation level (including mono-, di-, and trimethylaiton) ...
ORGANISM(S): Homo Sapiens 
2019-12-17 | PXD016779 |
ProteomicsMass spectrometry identification results of host proteins interacting with the NS1 protein of influenza B virus BYam-2018
Mass spectrometry identification results of host proteins interacting with the NS1 protein of influenza B virus BYam-2018
ORGANISM(S): Homo Sapiens 
2026-02-09 | PXD074269 |
UnknownUltrabright ratiometric Raman-guided epilepsy surgery by intraoperatively visualizing proinflammatory microglia.
Not available
S-EPMC12208331 | biostudies-literature
ProteomicsGlobal Profiling of RNA-Binding Protein Target Sites by LACE-seq
Proteomic analysis of Ago2-/- oocytes revealed that Ago2 interacted with endogenous small interfering RNAs (endo-siRNAs) to repress mRNA translation globally.
ORGANISM(S): Mus Musculus 
2021-05-07 | PXD025846 |
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