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ProteomicsAn integrated metabolomics and lipidomics approach for the study of metabolic network and early diagnosis in cerebral infarction
Cerebral infarction (CI) remains a major cause of high mortality and long-term disability worldwide. The exploration of biomarkers and pathogenesis is crucial for early diagnosis of CI. Although the understanding of metabolic perturbations underlying CI has increased in recent years, the relationshi...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036199 | Pride
Metabolomics Cerebral infarction Lc-ms Lipidomics Biomarkers 
UnknownLipoprotein(a) is a new prognostic factor in patients with psoriasis and coronary artery disease: a retrospective cohort study.
Not available
S-EPMC10474627 | biostudies-literature
MetabolomicsThe Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis

BACKGROUND: Manchurian walnut (Juglans mandshurica Maxim.) is a tree with multiple industrial uses and medicinal properties in the Juglandaceae family (walnuts and hickories). J. mandshurica produces juglone, which is a toxic allelopathic agent and has potential utilization value...

2022-05-18 | MTBLS3657 | MetaboLights
UnknownDiabetes is associated with a poor prognosis in patients with psoriasis and coronary artery disease.
Not available
S-EPMC12257814 | biostudies-literature
ProteomicsPMs-Ti4+-based plasma extracellular vesicles glycoproteomics and its application in lung cancer
PMs-Ti⁴⁺ enables glycoproteomic analysis that integrates EVs capture and in-situ enzymatic digestion. It can directly identify intact N-glycopeptides in plasma EVs. This study reveals protein expression and glycosylation remodeling in plasma EVs from lung cancer
ORGANISM(S): Homo Sapiens 
PXD076361 |
TranscriptomicsMicroRNA Directly Enhances Mitochondrial Translation during Muscle Differentiation.
MicroRNAs are well known to mediate translational repression and mRNA degradation in the cytoplasm. Various microRNAs have also been detected in membrane-compartmentalized organelles, but the functional significance has remained elusive. Here we report that miR-1, a microRNA specifically induced dur...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-57596 | biostudies-arrayexpress
ProteomicsMultifaceted insights into the environmental adaptability of Arnebia guttata under drought stress
Introduction: Global warming has led to increased environmental stresses on plants, notably drought. This affects plant distribution and species adaptability, with some medicinal plants showing enhanced drought tolerance and increased medicinal components. In this pioneering study, we delve into the...
ORGANISM(S): Arnebia Guttata 
PXD052741 |
ProteomicsProteoform Imaging by Combining MALDI MSI and High-sensitivity Top-down Proteomics
Spatially resolved characterization of proteoforms has great potential to significantly advance our understanding of physiological and disease mechanisms. However, it faces challenges regarding throughput and coverage. Herein, we developed a robust method for high-throughput proteoform imaging (HTPi...
ORGANISM(S): Mus Musculus 
2024-12-03 | PXD058552 |
ProteomicsIdentification and sequencing of CD36 interacting proteins in cardiomyocytes
Identification and sequencing of CD36 interacting proteins in cardiomyocytes
ORGANISM(S): Mus Musculus 
PXD056711 |
ProteomicsStudy on the spatial effect of peripheral ApoE3 on regulating cadmium binding proteome and mechanism of cognitive impairment in the elderly
The experiment utilized a total of 54 five-week-old Sprague-Dawley rats, each weighing approximately 100 grams. These rats were randomly divided into 9 groups, consisting of 27 female and 27 male rats. Based on the intervention dose of cadmium (Cd), the rats were further randomly assigned into 3 mai...
ORGANISM(S): Rattus Rattus 
PXD063013 |
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