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Protein methylation plays important roles in DNA damage signaling. To date, there is still a lack of global profiling of whole-cell methylation changes during the DNA damage response and repair. In this study, using HILIC affinity enrichment combined with MS analysis, we conducted a quantitative ana...
ORGANISM(S): Homo Sapiens 
2022-02-14 | PXD031655 |
Raw milk usually needs to be refrigerated at 4℃ before production, and microbial contamination during this process can cause spoilage of refrigerated raw milk. However, there is currently almost no research on plateau characteristic milk (yak milk and cattle-yak milk) (YM and CYM). In this study, si...
ORGANISM(S): Bos Taurus 
2024-03-22 | PXD050886 |
Background: Cardiovascular diseases remain the leading cause of morbidity and mortality worldwide, most of which are caused by atherosclerosis. Discerning processes that participate in macrophage-to-foam cell formation are critical for understanding the basic mechanisms underlying atherosclerosis. T...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD028363 | Pride
The interaction between peptide ligands and protein receptors induced significant abundance changes of the target proteins, which was a signature to indicate the interaction and provide complementary information for the current thermal proteome profiling (TPP) technique
ORGANISM(S): Homo Sapiens 
2022-01-26 | PXD031246 |
There have been reports of long coronavirus disease (long COVID) and breakthrough infections (BTIs); however, the mechanisms and pathological features of long COVID after Omicron BTIs remain unclear. Assessing long COVID and immune recovery after Omicron BTIs is crucial for understanding the disease...
ORGANISM(S): Homo Sapiens 
2023-08-08 | PXD044441 |
To determine how ZIKV hijacks host-protein signaling, a global quantitative proteomics experiment was performed in A549 cells. Cells were harvested in biological triplicate at four time points post-ZIKV infection (0, 24, 48, or 72 hours). Employing a tandem mass tag(TMT)-based proteomics approach, w...
ORGANISM(S): Homo Sapiens 
2024-03-13 | PXD050573 |
Unsaturated fatty acids (UFAs) in beef are essential for human health. Long-chain fatty acyl-CoA synthase 1 (ACSL1) is a crucial gene for UFAs synthesis in bovine adipocytes. To assess the protein expression profile during UFAs synthesis, we performed a proteomic analysis of bovine adipocytes by RNA...
ORGANISM(S): Bos Taurus 
2024-03-15 | PXD050702 |
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