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UnknownRegulation of CARD8 expression by ANRIL and association of CARD8 single nucleotide polymorphism rs2043211 (p.C10X) with ischemic stroke.
Not available
S-EPMC3962686 | biostudies-literature
TranscriptomicsGenome-wide analysis reveals dynamic changes in microRNAs expression during vascular cambium development in Chinese fir
MicroRNAs (miRNAs) are small noncoding regulatory RNAs that play key roles in the process of plant development. To date, extensive studies of miRNAs have been performed in a few model plants, but few efforts have focused on small RNAs in conifers because of the lack of reference sequences for these ...
ORGANISM(S): Cunninghamia lanceolata 
2015-04-07 | E-GEOD-53933 | biostudies-arrayexpress
ProteomicsA Stress-Adaptive Lipid Kinase Axis Defines Metabolic Vulnerabilities in Neuroendocrine Prostate Cancer
Neuroendocrine prostate cancer (NEPC) persists in a profoundly hypoxic microenvironment, yet the mechanisms enabling tumor adaptation to this metabolically challenging niche remain undefined. Here, we identify the lipid kinase PIKfyve as overexpressed in NEPC, functioning as a central node in a stre...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD076640 | Pride
ProteomicsQuantitative Proteomics Reveal the Protective Effects of CuraUltra Against Alzheimer’s Disease via Modulating the Expression of Synapse-associated Proteins in Mouse Model
To identify the potential molecular mechanism responsible for the effect on CuraUltra treatment, label-free quantitative proteomics by tandem mass spectrometry (LC-MS / MS) were performed, which provides in depth characterization of protein profile changes . Critical altered proteins were validated ...
ORGANISM(S): Mus Musculus 
2021-11-10 | PXD029640 |
TranscriptomicsHuman Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming
We generated induced human hepatocyte by transduction of several lineage specific transcription factors and analyzed the gene expression profile of generated hepatocytes and freshly isolated human hepatocytes through RNA sequencing. Global gene expression profile analysis
ORGANISM(S): Homo sapiens 
2014-03-10 | E-GEOD-54066 | biostudies-arrayexpress
MetabolomicsClinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats.

OBJECTIVE: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.

METHOD...

2024-03-25 | MTBLS5667 | MetaboLights
ProteomicsComparative Analysis of Soybean Seed Proteome Based on Different Mass Spectrometry Acquisition Strategies
This study established a soybean seed proteome database and analyzed the raw mass spectrometry data of BoxCar and DIA on MaxQuant based on this database. Subsequently, the three mass spectrometry acquisition strategies, DDA, DIA and BoxCar, were compared for their depth of protein identification, da...
ORGANISM(S): Glycine Max 
2024-05-16 | PXD052278 |
ProteomicsWFDC12 psoriasis disease and Proteomics
A role for whey acidic protein four-disulfide-core 12 in the pathogenesis and development of psoriasis disease
ORGANISM(S): Mus Musculus 
2022-08-23 | PXD036247 |
Proteomicsproteomic analysis of heteromorphic leaves in Populus euphratica through iTRAQ
This project employed iTRAQ to identify proteins in three types of heteromorphic leaves in Populus euphratica
ORGANISM(S): Populus Euphratica 
2020-03-01 | PXD011819 |
ProteomicsUrinary Proteomic Profiles of Anterior Cruciate Ligament Reconstruction Patients
A total of 30 ACLR patients, at least 9 months post-surgery, were recruited. Patients were divided into RTS and non-RTS groups based on their ability to return to sport, recovery to pre-injury Tegner levels, and a leg symmetry index of 85% on the single-leg hop test. Urine samples were analyzed usin...
ORGANISM(S): Homo Sapiens 
2025-02-19 | PXD060941 |
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