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UnknownSlightly acidic electrolyzed water as an alternative disinfection technique for hatching eggs.
Conventional chemical disinfectants used for egg disinfection could result in toxic residue and endanger hatchability, chick quality, and pullet growth performance. Slightly acidic electrolyzed water (SAEW) is known as a novel disinfectant for egg sterilization due to its high efficiency and no resi...
S-EPMC8749287 | biostudies-literature
UnknownMolecular characterization and immune functional analysis of IRF2 in common carp (Cyprinus carpio L.): different regulatory role in the IFN and NF-κB signalling pathway.

Background

Interferon regulatory factor 2 (IRF2) is an important transcription factor, which can regulate the IFN response and plays a role in antiviral innate immunity in teleost.

Results

In the present study, the full-length cDNA sequence of IRF2 (CcIRF2) was characterized in common...
S-EPMC8428054 | biostudies-literature
MetabolomicsLsr2, a novel cyclic di-GMP receptor, regulate the synthesis of keto-mycolic acid and control biofilm formation in mycobacteria

Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
UnknownHemagglutinin stalk-based monoclonal antibody elicits broadly reactivity against group 1 influenza A virus.

Background

Influenza virus remains a continuous and severe threat to public health worldwide, and its prevention and treatment have always been a major international issue. Because of its ability to evade immune surveillance through rapid antigenic drift and antigenic shift, broad-spectrum v...
S-EPMC7720065 | biostudies-literature
TranscriptomicsRNA-seq of Huh7 cell after G6PD enzyme activity inhibitor RRx-1 treated with 20μM concentrations for 24h
In order to analyze the changes of G6PD enzyme activity regulating the metabolism and proliferation pathways in HCC cell. After G6PD enzyme activity inhibitor RRx-1 treated with 20μM concentrations for 24h in Huh7 cell. Differential expression of genes were selected after RNA sequencing. Then David...
ORGANISM(S): Homo sapiens 
2020-11-12 | E-MTAB-9712 | biostudies-arrayexpress
ProteomicsOrthogonal Ionic Liquid-based Extraction Strategy Enables Amyloid-Specific Profiling of the Aggregate Proteome
Amyloid deposits are key pathological features of neurodegenerative diseases, yet their structural heterogeneity coupled with a stable β-sheet fibrillar architecture makes them extremely insoluble and difficult to isolate. Through systematic screening and molecular dynamics simulations, we identifie...
ORGANISM(S): Mus Musculus 
PXD069689 |
ProteomicsMolecular characterization of advanced colorectal cancer using serum proteomics and metabolomics
To comprehensively reveal molecular characterization of advanced CRC, we applied integrated proteomic and metabolomic analyses on serum samples from 20 patients with CRC at stage III or IV. Methods In the present study, we took advantage of nanoscale liquid chromatography and quadrupole time-of-flig...
ORGANISM(S): Homo Sapiens 
PXD025041 |
Genomicsena-DATASET-BGI-18-06-2015-05:57:10:511-19 - samples
We sequenced 205 patients who were suffering NSCLC with Exome sequencing method.
EGAD00001001398 | EGA
Genomicsena-DATASET-BGI-18-06-2015-04:55:13:301-17 - samples
We sequenced 292 patients who were suffering NSCLC with Whole genome sequencing or Exome sequencing method.
EGAD00001001397 | EGA
UnknownPredictive value of 8-year blood pressure measures in intracerebral haemorrhage risk over 5 years.

Aims

The relationships between long-term blood pressure (BP) measures and intracerebral haemorrhage (ICH), as well as their predictive ability on ICH, are unclear. In this study, we aim to investigate the independent associations of multiple BP measures with subsequent 5-year ICH risk, as we...
S-EPMC7616516 | biostudies-literature
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