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MetabolomicsSulfadiazine Sodium Improves Dysfunctional Metabolomics in Toxoplasma gondii-infected Mice
Toxoplasma gondii is an obligate intracellular protozoan parasite that poses a severe threat to human health, especially those immune-compromised individuals. Sulfadiazine sodium (SDZ) is widely used for the treatment of human toxoplasmosis. However, systems biology researches on the therapeutic eff...
2019-06-18 | MTBLS852 | MetaboLights
UnknownCharacterization of Nine Compounds Isolated from the Acid Hydrolysate of Lonicera fulvotomentosa Hsu et S. C. Cheng and Evaluation of Their In Vitro Activity towards HIV Protease.
Not available
S-EPMC6943440 | biostudies-literature
UnknownDa Cheng Qi Decoction Alleviates Cerulein-Stimulated AR42J Pancreatic Acinar Cell Injury via the JAK2/STAT3 Signaling Pathway.
Not available
S-EPMC8053057 | biostudies-literature
UnknownTherapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation.
Not available
S-EPMC9842028 | biostudies-literature
UnknownRNA Transcripts in Human Ovarian Cells: Two-Time Cryopreservation Does Not Affect Developmental Potential.
Not available
S-EPMC10139221 | biostudies-literature
ProteomicsA PROTAC Targets Splicing Factor 3B1
The proteolysis-targeting chimera (PROTAC) is a new technology to degrade a target protein. However, its clinical application is limited currently by lack of chemical binders to target protein. For instance, it is still unknown, whether splicing factor 3B subunit 1 (SF3B1) is targetable by PROTACs. ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-08 | PXD024661 | Pride
Hela Tmtpro Protac Orbitrap lumos 
MetabolomicsTranscriptomic and metabolomic analyses reveal the differential accumulation of phenylpropanoids and terpenoids in hemp autotetraploid and its diploid progenitor

Background

Cannabis sativa, a dioecious plant that has been cultivated worldwide for thousands of years, is known for its secondary metabolites, especially cannabinoids, which possess several medicinal effects. In this study, we investigated the autopolyploidization effects on the biosynthes...
2023-09-21 | MTBLS6032 | MetaboLights
ProteomicsQuantitative TMT proteomics of brainstem in spontaneously hypertensive rats
The brainstem, the core of the central nervous system, plays a vital role in controlling arterial blood pressure and its elevation of hypertension subtypes, especially essential hypertension. Integrative metabolic and proteomic profiling was performed on the brainstem samples of 11-week-old spontane...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-09-24 | PXD021210 | Pride
Quantitative proteome Tmt Brainstem Spontaneously hypertensive rats/shr rats 
UnknownMining of prognosis-related genes in cervical squamous cell carcinoma immune microenvironment.
Not available
S-EPMC7450998 | biostudies-literature
UnknownEpigenetic regulation of FOXI2 promotes clear cell renal cell carcinoma progression.
Not available
S-EPMC11016964 | biostudies-literature
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