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ProteomicsAnalysis of muscular proteomics of deep pressure ulcers reveals JAK2 influence on muscle autophagy and apoptosis
Pressure ulcers (PU) is a complex and serious clinical problem. Deep tissue injury is either the outcome or the trigger of deep PU. However, the cellular and molecular mechanisms that contribute to the pathogenesis of deep PU remain unclear. In this study, the degeneration characteristics, increased...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD009512 | Pride
Proteomics Ischemia/reperfusion injury Deep pressure ulcers Jak2 Autophagy & apoptosis 
ProteomicsMedium from human iPSC-derived primitive macrophages promote adult cardiomyocyte proliferation and cardiac regeneration
human induced pluripotent stem cell (hiPSC)-derived primitive macrophages (hiPMs) and their conditioned medium (hiPM-CM) promote human cardiomyocyte proliferation and to enhance cardiac regeneration in infarcted adult mouse hearts. To identify the components underlying the pro-proliferative effects ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD057702 | Pride
Human Macrophage Conditioned medium Lc-ms/ms 
ProteomicsTMT-Based Quantitative Proteomics Reveals Implication of a Late Embryogenesis Abundant Protein (BnLEA57) In Seed Oil Accumulation in Brassica napus L.
Enhancing oil content is one of the major goals in Brassica napus breeding, however, genetic regulation of seed oil content in plants is complex and not fully elucidated. In the present study, we report proteins that were differentially accumulated in immature seeds of 35 days after anthesis between...
ORGANISM(S): Brassica Napus 
PXD033185 |
ProteomicsStructural mass spectrometry captures residue-resolved comprehensive conformational rearrangements of a G protein-coupled receptor
GPCR structural studies with in-solution spectroscopic approaches have offered distinctive insights into GPCR activation and signaling that highly complement those yielded from structural snapshots by crystallography or cryo-EM. While most current spectroscopic approaches excel at probing structural...
ORGANISM(S): Homo Sapiens 
PXD048942 |
ProteomicsLabel-free proteomics of endometrial epithelial cell for identification of presumptive biomarkers of endometritis
A total of 1180 proteins were identified in the control group and endometritis model group, of which 313 differential proteins were accurately quantified. The proteomic results were verified by WB, TEC and IF techniques, and the same conclusion was obtained.
ORGANISM(S): Capra Hircus 
2022-05-18 | PXD033950 |
ProteomicsApolipoprotein E as a potential biomarker of moyamoya disease
The underlying mechanisms of moyamoya disease (MMD) remain unclear, and there is a lack of effective biomarkers. This study aimed to identify novel serum biomarkers of MMD.
ORGANISM(S): Homo Sapiens 
2023-02-08 | PXD039975 |
ProteomicsProteomic study on lavage fluid of Dairy cows 30 days after delivery
Lipopolysaccharide (LPS) is a component of the outer membrane of gram-negative bacteria that is involved in pathogenic processes leading to postpartum metritis and endometritis in dairy cow. It also causes inflammation of the endometrium. This study aimed to investigate the effects of LPS on cow end...
ORGANISM(S): Bos Taurus 
2022-08-23 | PXD036248 |
ProteomicsIntegrated proteomic and transcriptomic analyses reveal the roles of Brucella BI-1 in cell division and membrane homeostasis of Brucella suis S2
To explore the role of Brucella BI-1 in Brucella suis S2, we constructed the Brucella BI-1 deletion mutant strain and its complementary strain. We then determined the effect of Brucella BI-1 deletion on the physiological characteristics of Brucella suis S2 and revealed them via integrated transcript...
ORGANISM(S): Brucella Suis Bv. 1 Str. S2 
2020-11-13 | PXD022537 |
ProteomicsTargeting Lipid raft-related stomatin strategy for challenging osteoporosis
Mouse bone marrow macrophages, with or without the addition of RANKL, are being investigated for their interactions with proteins that associate with the stomatin protein.
ORGANISM(S): Mus Musculus 
2025-03-13 | PXD061779 |
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