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The anaerobic, spore-forming pathogen Clostridioides difficile infects the gastrointestinal tract of higher mammals, including humans, and is the major causative agent of antibiotic-associated diarrhea. Moreover, recurrence and re-infection rates after a first successful antibiotic therapy are subst...
ORGANISM(S): Peptoclostridium difficile (strain 630) (Clostridium difficile) 
2023-03-29 | PXD029243 | Pride
Comparing differential expressed proteins between Mycoplasma bovis different strains by using label-free method
ORGANISM(S): Mycoplasma bovis HB0801 
2020-06-15 | PXD017374 | Pride
Fidaxomicin is considered the current gold standard antibiotic for treating Clostridioides difficile infections and kills bacterial cells by inhibition of the RNA polymerase through binding to its switch region. Although binding sites do not overlap, also Myxopyronin B inhibits the RNA polymerase by...
ORGANISM(S): Peptoclostridium difficile (strain 630) (Clostridium difficile) 
2021-12-21 | PXD027366 | Pride
Pluripotency-associated transcription factor Foxd3 is required for maintaining pluripotent cells. However, the molecular mechanisms underlying its function are largely unknown. Here, we report that Foxd3 maintains the ESC identity through counteracting differentiation induction of Calcienurin-NFAT s...
ORGANISM(S): Mus musculus 
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