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UnknownThe crystal structure of GH57 family amylopullulanase reveals its dual binding pockets sharing the same catalytic dyad.
Not available
S-EPMC12106739 | biostudies-literature
TranscriptomicsTranscription profiling by high throughput sequencing of methamphetamine-sensitized and saline-control mouse nucleus accumbens
Using ssRNA-seq, we examined the alteration of transcription profiles in the nucleus accumbens of methamphetamine-sensitized mice. Methamphetamine was a commonly abused psychostimulant. Repeated exposure to methamphetamine elicited long-lasting cellular and molecular changes, including the aberrant ...
ORGANISM(S): Mus musculus 
2017-01-15 | E-MTAB-2843 | biostudies-arrayexpress
ProteomicsTumor-Derived Exosomal CCT6A Serves as a Matchmaker Introducing Chemokines to Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma
CCT6A is a key subunit of the TRiC complex and is responsible for the folding and maturation of approximately 10% of newly synthesized proteins in cells. Given that different TRiC subunits exhibit substrate specificity, we hypothesized that CCT6A might act as a specific binding subunit. To test this...
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD057101 | Pride
Human  pdac cell line  lc-ms  knockdown of cct6a 
ProteomicsTumor-Derived Exosomal CCT6A Serves as a Matchmaker Introducing Chemokines to Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma
M2-polarized tumor-associated macrophages (TAMs) are a key factor contributing to the poor prognosis of pancreatic ductal adenocarcinoma (PDAC). While various factors within the tumor microenvironment drive their formation, the role of PDAC-derived exosomes in this process remains unclear. We aim to...
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD056403 | Pride
Exosome Cct6a Pdac 
ProteomicsCreation of a Plant Metabolite Spectral Library for Untargeted and Targeted Metabolomics
Large-scale high throughput metabolomic technologies are indispensable components of systems biology in terms of discovering and defining the metabolite parts of the system. However, the lack of a plant metabolite spectral library limited the metabolite identification of plant metabolomics study. He...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2022-12-03 | MSV000090829 | MassIVE
UnknownA wearable echomyography system based on a single transducer.
Not available
S-EPMC12269893 | biostudies-literature
ProteomicsiTRAQ-Based Proteomic Analysis Reveals Potential Serum Biomarkers for Pediatric Non-Hodgkin’s Lymphoma
This study aimed to screen and verify potential serum biomarkers of pediatric NHL using isobaric tags for relative and absolute quantification (iTRAQ)-based proteomic analysis. Serum protein expression profiles from children with B-NHL (n=20) and T-NHL (n=20) and healthy controls (n=20) were detecte...
ORGANISM(S): Homo Sapiens 
2022-03-16 | PXD032308 |
Proteomicsthe function of RNA Binding Protrein in cancer
RNA Binding Protrein plays of vital imortance in cancer progression.
ORGANISM(S): Homo Sapiens 
2021-12-08 | PXD022776 |
UnknownChanges in Home Blood Pressure Monitored Among Elderly Patients With Hypertension During the COVID-19 Outbreak: A Longitudinal Study in China Leveraging a Smartphone-Based Application.
Not available
S-EPMC8136456 | biostudies-literature
ProteomicsNanoparticle-loaded antigenic components
e dissolved eight antigenic nanoparticles to release their loaded components and assayed the protein species in them
ORGANISM(S): Homo Sapiens 
2024-05-25 | PXD052576 |
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