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TranscriptomicsRNAseq of HCT116 p53KO cells transfected with either siRNA silencing ZNF84 or with negative control siRNA, in 2 variants of experiment a) with doxorubicin treatment (doxorubicin added 48h post-transfection, for the next 48h before harvesting) b) untreated, cultured 72h post-transfection
The aim of this experiments was to characterise the transcriptomic changes occurring in cancer cells, in which ZNF84 gene is silenced, in control conditions and when cells undergo stress by being treated with cytostatic doses of doxorubicin. We anticipated that ZNF84 regulates the level of p21 cell ...
ORGANISM(S): Homo sapiens 
2021-05-05 | E-MTAB-9848 | biostudies-arrayexpress
UnknownChromatin-Directed Proteomics Identifies ZNF84 as a p53-Independent Regulator of p21 in Genotoxic Stress Response.
Not available
S-EPMC8123910 | biostudies-literature
ProteomicsIdentification of chromatin-associated proteins occupying the promoter region of CDKN1A
The p21 protein, encoded by CDKN1A, plays a vital role in the induction of senescence, and its transcriptional control by p53 tumour supressor is well-established. However, p21 can also be regulated in a p53-independent manner, by mechanisms that remain poorly understood. Therefore, we here used a c...
ORGANISM(S): Homo sapiens (Human) 
2021-09-07 | PXD022542 | Pride
Cdkn1a Znf84 Chromatin-associated proteins 
GenomicsRNAseq of HCT116 p53KO cells transfected with either siRNA silencing ZNF84 or with negative control siRNA, in 2 variants of experiment a) with doxorubicin treatment (doxorubicin added 48h post-transfection, for the next 48h before harvesting) b) untreated, cultured 72h post-transfection
RNAseq of HCT116 p53KO cells transfected with either siRNA silencing ZNF84 or with negative control siRNA, in 2 variants of experiment a) with doxorubicin treatment (doxorubicin added 48h post-transfection, for the next 48h before harvesting) b) untreated, cultured 72h post-transfection
PRJEB41676 | ENA
GenomicsTF ChIP-seq from K562 (ENCSR376UMR)
eGFP-ZNF84 ChIP-seq on human K562 For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2021-03-30 | GSE170702 | GEO
GenomicsControl ChIP-seq from K562 (ENCSR796QVL)
K562 immortalized cell line stably expressing C-terminal eGFP-ZNF84 fusion protein. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2022-07-22 | GSE209162 | GEO
TranscriptomicsTranscription profiling of human mature oocytes and embryonic stem cells reveals overexpression of the proteasome pathway
The first week of human pre-embryo development is characterized by the induction of totipotency and then pluripotency. The understanding of this delicate process will have far reaching implication for in vitro fertilization and regenerative medicine. Human mature MII oocytes and embryonic stem (ES) ...
ORGANISM(S): Homo sapiens 
2009-01-16 | E-GEOD-11450 | biostudies-arrayexpress
UnknownUnveiling differentially expressed genes upon regulation of transcription factors in sepsis.
Not available
S-EPMC5428098 | biostudies-literature
UnknownA gene expression signature shared by human mature oocytes and embryonic stem cells.
Not available
S-EPMC2628676 | biostudies-literature
TranscriptomicsTranscriptome analysis of human mature oocytes and embryonic stem cells reveals overexpression of the proteasome pathway
The first week of human pre-embryo development is characterized by the induction of totipotency and then pluripotency. The understanding of this delicate process will have far reaching implication for in vitro fertilization and regenerative medicine. Human mature MII oocytes and embryonic stem (ES) ...
ORGANISM(S): Homo sapiens 
2009-01-12 | GSE11450 | GEO
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