Sort   by:  
 Page size 
ProteomicsInhibition of melanization activation by Serpin-5 and Serpin-9 promotes nucleopolyhedrovirus infection in cotton bollworm Helicoverpa armigera
One of important insect defense mechanisms is melanization, which are mediated by clip domain serine protease (cSP) cascades and regulated by Serpins. In vitro, activation of melanization can efficiently kill Nucleopolyhedrovirus (NPV). However, quantitative proteomics revealed that the infection of...
ORGANISM(S): Helicoverpa armigera (Cotton bollworm) 
2017-09-19 | PXD006126 | Pride
Prophenoloxidase Hemolymph Cotton bollworm Serpin Melanization 
ProteomicsDynamics of the interaction between cotton bollworm Helicoverpa armigera and nucleopolyhedrovirus as revealed by integrated transcriptomic and proteomic analyses
Over the past decades, Helicoverpa armigera nucleopolyhedrovirus (HearNPV) has been widely used for biocontrol of cotton bollworm, which is one of the most destructive pest insects in agriculture worldwide. However, the molecular mechanism underlying the interaction between HearNPV and host insects ...
ORGANISM(S): Helicoverpa armigera (Cotton bollworm) 
2017-04-19 | PXD004748 | Pride
Cotton bollworm Insect immunity Carbohydrate metabolism Baculovirus Host-pathogen interaction Fat body Rna-seq Lc-ms/ms 
TranscriptomicsTranscription profiling of Arabidopsis pollen germination and tube growth
Pollen germination, along with pollen tube growth, is an essential process for the reproduction of flowering plants. The germinating pollen with tip-growth characteristics provides an ideal model system for the study of cell growth and morphogenesis. As an essential step towards a detailed underst...
ORGANISM(S): Arabidopsis thaliana 
2008-10-25 | E-GEOD-6696 | biostudies-arrayexpress
ProteomicsMicroplitis mediator venom protein LC-MSMS
Insects mount an innate immune response to defend against the foreign invading microorganisms and parasites. To be successful parasites, endoparasitoid wasps need to be able to suppress the immune responses of their hosts. This allows the wasp eggs to hatch and the larvae to develop inside the host....
ORGANISM(S): Microplitis mediator 
2019-01-07 | PXD007905 | Pride
Lc-msms Venom Micrioplitis mediator 
ProteomicsAedes aegypti CLIPB9 activates prophenoloxidase-3 in the presence of CLIPA14 after fungal infection
Melanization is an integral part of the insect defense system and is often induced by pathogen invasion. Phenoloxidases (POs) are critical enzymes that catalyze melanin formation. PO3 is associated with the antifungal response of the mosquito, Aedes aegypti, but the molecular mechanism of the prophe...
ORGANISM(S): Aedes aegypti 
2022-07-21 | PXD033507 | Pride
Serine protease Serine protease homolog Antifungal response Immune melanization Prophenoloxidase 
ProteomicsiTRAQ-based proteomic analysis of female Aedes aegypti mosquitoes during reproduction
iTRAQ data reveal the distribution and the level of proteins during mosquito reproductive cycle.
ORGANISM(S): Aedes Aegypti 
2025-05-23 | PXD064277 |
UnknownsiRNA-mediated suppression of collagen type iv alpha 2 (COL4A2) mRNA inhibits triple-negative breast cancer cell proliferation and migration.
Not available
S-EPMC5356825 | biostudies-literature
ProteomicsOTU7B modulates the mosquito immune response to Beauveria bassiana infection via deubiquitination of the Toll adaptor TRAF4
Insects use innate immunity to defend microbial infection. Toll pathway is a major immune signaling pathway that is associated with antifungal immune response in mosquitoes. Our study identified a fungal-induced deubiquitinase, OTU7B, which, when knocked out, promotes the translocation of the NF-κB ...
ORGANISM(S): Aedes Aegypti 
2022-11-22 | PXD038261 |
ProteomicsSuppression of mosquito Aedes aegypti population using a CRISPR-targeted leucine aminopeptidase 1 mutation
Aedes aegypti are vectors of several devastating arboviruses infecting hundreds of millions of people annually. Controlling mosquito populations by regulating their reproduction is important to minimize viral transmission in the absence of effective antiviral therapies or vaccines. Here, we demonstr...
ORGANISM(S): Aedes Aegypti 
2023-02-05 | PXD039869 |
UnknownIdentification of key genes and pathways associated with gender difference in osteonecrosis of the femoral head based on bioinformatics analysis.
Not available
S-EPMC9976184 | biostudies-literature
Sort   by:  
 Page size