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TranscriptomicsTranscription profiling of primary hippocampal neurons isolated from mouse E17 embryos and undergoing differentiation in the culture for 7h, 18h, 33h, 72h, 8 days, 12 days (at which time points the RNA was extracted) vs RNA isolated from a newborn brain
A time-course experiment, in which the gene expression in the primary hippocampal neurons isolated from E17 embryos and undergoing differentiation in the culture for 7h, 18h, 33h, 72h, 8 days, 12 days (at which time points the RNA was extracted) was compared by competitive hybridization with a commo...
ORGANISM(S): Mus musculus 
2003-06-01 | E-MEXP-11 | biostudies-arrayexpress
ProteomicsAblation of mitochondrial rhomboid Parl causes Leigh syndrome
The mitochondrial intramembrane rhomboid protease Parl plays essential roles in cell death but its physiological contribution remains unclear. In the present study we show that Parl ablation causes a dramatic necrotic neurodegeneration consistent with Leigh syndrome, a mitochondrial disease characte...
ORGANISM(S): Mus musculus (Mouse) 
2018-11-21 | PXD008908 | Pride
Leigh syndrome Pgam5 Rhomboids Proteolysis Necrosis Ttc19 Complex iii Apoptosis Neurodegeneration Parl Pink1 
UnknownModernization of Golgi staining techniques for high-resolution, 3-dimensional imaging of individual neurons.
Not available
S-EPMC6333844 | biostudies-literature
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