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Macrophages represent a major immune cell population in atherosclerotic plaques and play central role in the progression of this lipid-driven chronic inflammatory disease. Targeting immunometabolism is proposed as a strategy to revert aberrant macrophage activation to improve disease outcome. Here, ...
2021-03-05 | MTBLS2159 | MetaboLights
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
The LIM-domain-only protein FHL2 is a modulator of signal transduction and has been shown to direct the differentiation of mesenchymal stem cells toward osteoblasts and myocytes phenotypes. We hypothesized that FHL2 may simultaneously interfere with the induction of the adipocyte lineage. Therefore,...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-13 | PXD033974 | Pride
Two Zygnematophyceaen algae (sister-clade of the Embryophytes) were investigated: Mesotaenium endlicherianum SAG12.97 and Zygnema circumcarinatum SAG698-1b. The algae were grown on agar plates and submitted to osmotic stress for 6 or 25 hours by transferring them to a plates supplemented with either...
ORGANISM(S): Zygnema circumcarinatum Mesotaenium endlicherianum 
2025-08-12 | PXD060327 | Pride
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