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ProteomicsMechanism of chaperone coordination during cotranslational protein folding in bacteria
Protein folding is assisted by molecular chaperones that bind nascent polypeptides during mRNA translation. Several structurally-distinct classes of chaperone promote de novo folding, suggesting that their activities are coordinated at the ribosome. We used biochemical reconstitution and structural ...
ORGANISM(S): Escherichia coli 
2024-07-03 | PXD048623 | Pride
Nascent chain Ribosomes Xl-ms Molecular chaperones Protein synthesis Β-galactosidase Protein folding 
UnknownReducing Inequalities in Timing of Antenatal Care Initiation: A Hypothetical Intervention in the Generation R Study.
Not available
S-EPMC12391855 | biostudies-literature
UnknownAccelerating the transition from a linear to a circular healthcare sector: ESCH-R: study design and methodology.
Not available
S-EPMC11978829 | biostudies-literature
UnknownPrognostic and predictive performance of R-ISS with SKY92 in older patients with multiple myeloma: the HOVON-87/NMSG-18 trial.
Not available
S-EPMC7756986 | biostudies-literature
UnknownSpatial and temporal variation of five different pathogens and symbionts in Ixodes ricinus nymphs in the Netherlands.
Not available
S-EPMC11414485 | biostudies-literature
Proteomicshuman MS Lesions ABPP - foamy microglia link oxylipins to disease progression in multiple sclerosis
In this study lesions from human MS brains and controls were isolated and analyzed by Activity-based protein profiling using fluorophosphonate- and beta-lacton probes to enrich active enzymes from the samples. these were subsequently analyzed by LC/MS-MS.
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD056899 | Pride
Multiple sclerosis Activity-based protein profiling Serine hydrolase Lesions Brain Chemical proteomics Fluorophosphonate 
MetabolomicsExploring the Fecal Metabolome in Infants With Cow's Milk Allergy: The Distinct Impacts of Cow's Milk Protein Tolerance Acquisition and of Synbiotic Supplementation.

SCOPE: Cow's milk allergy (CMA) is one of the most prevalent food allergies in early childhood, often treated via elimination diets including standard amino acid-based formula or amino acid-based formula supplemented with synbiotics (AAF or AAF-S). This work aimed to assess ...

2024-09-02 | MTBLS8954 | MetaboLights
TranscriptomicsMacrophage heterogeneity in human carotid artery atherosclerotic plaques: identification of novel markers for M1 and M2 that are independent of the activation status
Recent studies suggest the presence of both “classically activated” M1 and “alternatively activated” M2 macrophages in human atherosclerotic tissue, yet due to the lack of validated markers the reported localization patterns of these macrophage phenotypes within plaques are ambiguous. In the...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-22543 | biostudies-arrayexpress
UnknownAssociations between meeting the Canadian 24-hour movement guidelines and physical, cognitive, social-emotional, and overall development in early childhood.
Not available
S-EPMC11934447 | biostudies-literature
UnknownIncreased vascular smooth muscle cell senescence in aneurysmal Fibulin-4 mutant mice.
Not available
S-EPMC11189919 | biostudies-literature
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