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UnknownVitamin D supplementation in chronic obstructive pulmonary disease patients with low serum vitamin D: a randomized controlled trial.
Not available
S-EPMC9348978 | biostudies-literature
UnknownPrevention of exacerbations in patients with COPD and vitamin D deficiency through vitamin D supplementation (PRECOVID): a study protocol.
Not available
S-EPMC4580355 | biostudies-literature
TranscriptomicsNickel and binary metal mixtures in Daphnia magna after 96h
The recent development of a custom cDNA microarray platform for one of thé standard organisms in aquatic toxicology, Daphnia magna, opened up new ways to mechanistic insights of toxicological responses. In this study, gene expression and (sub)organismal responses (Cellular Energy Allocation, growt...
ORGANISM(S): Daphnia magna 
2010-05-22 | E-GEOD-13866 | biostudies-arrayexpress
TranscriptomicsDevelopment of a microarray for Enchytraeus albidus (Oligochaeta): Preliminary tool with diverse applications
Standard bioassays allow hazard assessment at the population level, but much remains to be learned about the molecular level response of organisms to stressors. The main aim of this study was the development of a DNA microarray for Enchytraeus albidus, a common soil worm species. Further, this micro...
ORGANISM(S): Enchytraeus albidus 
2011-03-30 | E-GEOD-18569 | biostudies-arrayexpress
TranscriptomicsConcerted involvement of Cdx/Hox genes and Wnt signalling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone.
Decrease in Cdx dosage in an allelic series of mouse Cdx mutants leads to progressively more severe posterior vertebral defects. These defects are corrected by posterior gain of function of the Wnt effector Lef1. Precocious expression of Hox paralogous 13 genes also induces vertebral axis truncat...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-30113 | biostudies-arrayexpress
UnknownDevelopment and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study.
Not available
S-EPMC4380415 | biostudies-literature
TranscriptomicsA role for Multidrug Resistance Protein 4 (MRP4; ABCC4) in human Dendritic Cell migration.
The capacity of dendritic cells (DC) to migrate from peripheral organs to lymph nodes (LN) is an important event in the initiation of a T cell-mediated immune response. Previously it was shown that the ATP-binding cassette (ABC) transporters P-glycoprotein (P-gp; ABCB1) and the 2 multidrug resistanc...
ORGANISM(S): Homo sapiens 
2008-07-12 | E-GEOD-12089 | biostudies-arrayexpress
TranscriptomicsD. magna exposed to fluoranthene and pyrene - both as single compounds and binary mixtures
Daphnia are an important and widely studied model species in ecological and toxicological studies throughout the world and an official (OECD) recommended test organism. Their small size, wide distribution and easy growth conditions make this an organism ideal for functional genomics based studies, i...
ORGANISM(S): Daphnia magna 
2010-05-16 | E-GEOD-16869 | biostudies-arrayexpress
TranscriptomicsGene transcription profiles and potential transgenerational epigenetic effects related to Zn exposure history in Daphnia magna
A reduced level of DNA methylation has recently been described in both Zn-exposed and non-exposed offspring of Daphnia magna exposed to Zn. The hypothesis examined in this study is that DNA hypomethylation has an effect on gene transcription. A second hypothesis is that accumulative epigenetic effec...
ORGANISM(S): Daphnia magna 
2010-07-23 | E-GEOD-22805 | biostudies-arrayexpress
TranscriptomicsFlusilazole dose response in zebrafish embryo
The zebrafish embryotoxicity test (ZET) is considered as a useful alternative model in predictive toxicology. Currently, morphological assessment of the embryo is the main readout for this assay. However, implementation of transcriptomics may help to detect more subtle effects which may increase the...
ORGANISM(S): Danio rerio 
2012-03-21 | E-MTAB-832 | biostudies-arrayexpress
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