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UnknownmTOR signaling in liver regeneration: Rapamycin combined with growth factor treatment.
Not available
S-EPMC3832859 | biostudies-literature
ProteomicsCholangiocyte organoid culture in hydrogels from decellularized liver tissue
Culture of human cholangiocyte organoids in hydrogels derived from healthy liver extracellular matrix (LECM) extracts prepared from decellularized human livers are evaluated in an effort to establish a platform for production of cholangiocyte organoids for clinical regenerative applications. Human ...
ORGANISM(S): Homo sapiens (Human) 
2022-04-13 | PXD028417 | Pride
Human Regeneration Hydrogel Liver Cholangiocyte Organoid 
ProteomicsPatient-derived model combining organoids and matrix reveals cholangiocarcinoma promoting properties of the microenvironment
Cholangiocarcinoma (CCA) is a rare but aggressive type of primary liver cancer, with an overall 5-year survival rate of <10%. The extracellular matrix (ECM) plays a particularly important role in CCA tumor biology, manifested in the desmoplastic tumor environment. This study aim is to design an in v...
ORGANISM(S): Homo sapiens (Human) 
2023-03-04 | PXD028408 | Pride
Human Organoids Tissue culture Liver Cholangiocarcionoma Extracellular matrix 
ProteomicsProteome of human branching and non-branching cholangiocyte organoids
Current model systems for studying intrahepatic biliary disease fail to recapitulate the architecture of intrahepatic bile ducts. Organoids from intrahepatic cholangiocytes can with a new culture method grow with a branching pattern resembling the structure of intrahepatic bile ducts. This dataset c...
ORGANISM(S): Homo sapiens (Human) 
2022-05-09 | PXD028532 | Pride
Disease modelling Cholangiocyte organoids Cholangiocarcinoma Cholangiocytes Intrahepatic bile duct Branching morphogenesis Embryonic development 
UnknownValidation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery.
Not available
S-EPMC8855527 | biostudies-literature
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