Hartmann2016 - Blood coagulation model for simulating anticoagulants

ABSTRACT: Mathematical model of blood coagulation. Reused Wajima2009 model with modifications to reactions 27 (formation of Va:Xa complex), 32 (Xa inhibition by TFPI) and 45 (Xa inhibition by TFPI-Heparin complex) as described in publication equations 2,3 and 4. Publication lists parameter sets to simulate Rivaroxaban, VKA and Enoxaparin (supplementary files).

SUBMITTER: Matthew Roberts  

PROVIDER: MODEL1807180004 | BioModels | 2018-07-18

REPOSITORIES: BioModels