Models

Dataset Information

82

Makin2013 - Blood coagulation cascade model


ABSTRACT: Mathematical model of the blood coagulation system including lipid binding sites, meizothrombin, thrombomodulin, cleaved and light peptide chain Va species and Heparin.

SUBMITTER: Matthew Roberts  

PROVIDER: MODEL1807230001 | BioModels | 2018-07-23

REPOSITORIES: BioModels

altmetric image

Publications

A hybrid-system model of the coagulation cascade: simulation, sensitivity, and validation.

Makin Joseph G JG   Narayanan Srini S  

Journal of bioinformatics and computational biology 20130905 5


The process of human blood clotting involves a complex interaction of continuous-time/continuous-state processes and discrete-event/discrete-state phenomena, where the former comprise the various chemical rate equations and the latter comprise both threshold-limited behaviors and binary states (presence/absence of a chemical). Whereas previous blood-clotting models used only continuous dynamics and perforce addressed only portions of the coagulation cascade, we capture both continuous and discre  ...[more]

Similar Datasets

2019-07-10 | BIOMD0000000747 | BioModels
2018-07-23 | MODEL1807230003 | BioModels
2019-07-01 | BIOMD0000000739 | BioModels
2018-07-18 | MODEL1807180002 | BioModels
2018-07-18 | MODEL1807180004 | BioModels
2018-08-13 | MODEL1808130001 | BioModels
2018-06-07 | MODEL1806070001 | BioModels
| GSE109140 | GEO
2018-06-06 | MODEL1806060001 | BioModels
2019-07-12 | MODEL1907120001 | BioModels