Optical Coherence Tomography in Schizophrenia Spectrum Disorders: A Systematic Review and Meta-analysis.

ABSTRACT:

Background

Inner retinal atrophy has been demonstrated in schizophrenia spectrum disorder (SSD) using optical coherence tomography (OCT). This systematic review and meta-analysis investigated the role of contemporary Fourier domain OCT devices in SSD.

Methods

MEDLINE, PubMed, Scopus, Embase, PsycInfo, PYSNDEX, World Health Organization, and Cochrane databases were searched from inception until May 2022. All peer-reviewed adult SSD case-control studies using Fourier domain OCT were included. Ocular pathologies known to affect retinal OCT scans were excluded. Search, data appraisal, and summary data extraction were independently performed by 2 authors.

Results

The review criteria was met by k = 36 studies, with k = 24 studies (1074 cases, 854 controls) suitable for meta

SUBMITTER: Shew W 

PROVIDER: S-EPMC10654004 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature